Yatzidis H
Nephrological Center, University of Athens School of Medicine, Aretaieon Hospital, Greece.
Perit Dial Int. 1991;11(3):224-7.
This paper describes the use of glycylglycine to prepare dialysis solution containing bicarbonate, calcium and magnesium. Bicarbonate with glycylglycine form a buffer with a constant pH of 7.35, which prevents reaction with calcium or magnesium and the formation of insoluble carbonate salts. This bicarbonate-based solution is stable over long periods and can be used with the same simplicity and convenience as lactate solution for peritoneal dialysis (PD) in humans.
本文描述了使用甘氨酰甘氨酸制备含碳酸氢盐、钙和镁的透析液。碳酸氢盐与甘氨酰甘氨酸形成pH值恒定为7.35的缓冲液,可防止与钙或镁发生反应以及形成不溶性碳酸盐。这种基于碳酸氢盐的溶液长期稳定,在人体腹膜透析(PD)中使用时,其简便性和便利性与乳酸盐溶液相同。