血管样条纹和弹性假黄瘤中的脉络膜新生血管形成：1年随访
Choroidal neovascularization in angioid streaks and pseudoxanthoma elasticum: 1 year follow-up.
作者信息
Schiano Lomoriello D, Parravano M C, Chiaravalloti A, Varano M
机构信息
Fondazione G.B. Bietti-IRCCS, Roma, Italy.
出版信息
Eur J Ophthalmol. 2009 Jan-Feb;19(1):151-3. doi: 10.1177/112067210901900125.
PURPOSE
To report the efficacy of intravitreal injection of bevacizumab 1.25 mg (IVB) in the treatment of choroidal neovascularization (CNV) secondary to angioid streaks (AS).
METHODS
Case review of two patients with CNV secondary to AS treated with three IVB with a 1-year follow up.
RESULTS
In both patients after 1 year fluorescein angiography and optical coherence tomography showed complete inactivity of the CNV and the ophthalmologic examination revealed stabilization of the visual acuity.
CONCLUSIONS
The IBV appeared to be an effective and safe treatment for CNV secondary to AS resulting in a long-term CNV inactivation. Further long-term studies in this type of lesion are desirable.
目的
报告玻璃体内注射1.25毫克贝伐单抗（IVB）治疗血管样条纹（AS）继发脉络膜新生血管（CNV）的疗效。
方法
对2例AS继发CNV患者进行病例回顾，给予3次IVB治疗，并随访1年。
结果
1年后，两名患者的荧光素血管造影和光学相干断层扫描显示CNV完全静止，眼科检查显示视力稳定。
结论
IVB似乎是治疗AS继发CNV的一种有效且安全的方法，可导致CNV长期静止。对此类病变进行进一步的长期研究是必要的。
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