Nissim Ben Efraim A H, Levi-Schaffer F
Department of Pharmacology and Experimental Therapeutics, School of Pharmacy, Faculty of Medicine, The Hebrew University of Jerusalem, Israel.
Ther Adv Respir Dis. 2008 Jun;2(3):163-71. doi: 10.1177/1753465808092281.
This review covers the role of eosinophils in asthma-associated tissue remodeling and angiogenesis focusing on angiogenesis which is a recently discovered feature of asthma. In addition, novel directions for eosinophil-targeted/angiogenesis-targeted pharmacological intervention are discussed as new approaches in the treatment of asthma.
本综述涵盖了嗜酸性粒细胞在哮喘相关组织重塑和血管生成中的作用,重点关注血管生成,这是哮喘最近发现的一个特征。此外,还讨论了针对嗜酸性粒细胞/血管生成的药理干预的新方向,作为哮喘治疗的新方法。