Beuvon F, Criscuolo J L, Salmon R J, Laurent M
Laboratoire d'anatomie pathologique, institut Curie, Paris, France.
Bull Cancer. 1991;78(7):619-26.
The authors report on a case of radiation-induced malignant Triton tumor eg malignant schwannoma with rhabdomyoblastic differentiation). The tumor was situated in the brachial plexus of a patient who had received irradiation therapy 20 years previously for breast carcinoma. Pathological and immunohistological features have been described: coexpression of PS100, vimentin and desmin indicate a common neuroectodermic origin. A review of the literature has been presented in order to evaluate the diagnostic and prognostic characteristics of this unusual tumor and its relationship to neurofibromatosis.
作者报告了一例辐射诱发的恶性蝾螈瘤(即具有横纹肌母细胞分化的恶性神经鞘瘤)。该肿瘤位于一名20年前因乳腺癌接受放射治疗的患者的臂丛神经处。已描述了其病理和免疫组织学特征:PS100、波形蛋白和结蛋白的共表达表明其起源于共同的神经外胚层。为了评估这种不寻常肿瘤的诊断和预后特征及其与神经纤维瘤病的关系,已对相关文献进行了综述。