Selivanova A T
Zh Vyssh Nerv Deiat Im I P Pavlova. 1975 Jan-Feb;25(1):87-94.
In dogs with elaborated rhythmic and mozaic stereotypes of secretory and motor situational conditioned reflexes specific features were revealed in the action of some neurotropic drugs (amizyl, amedine, diphacil, pediphene, chlorpromazine and sodium oxybutyrate) on preparatory (latent) conditions of excitation and inhibition, appearing in the stabilized systems of reflexes. Pharmacological analysis has pointed to the predominantly cholinergic nature of preparatory and trigger mechanisms of alimentary conditioned activity. The blockade of M-cholinoreceptors (by means of amizyl and amedine) weakens or eliminates the preparatory conditions appearing in a dynamic stereotype and disturbs the trigger reactions within three to ten days. A pediphene blockade of H-cholinoreceptors intensifies the preparatory states.
在具有分泌性和运动性情境性条件反射的精细节律性和镶嵌式刻板模式的犬中，揭示了某些神经营养药物（阿米齐尔、阿美丁、双苯酰草胺、苯海拉明、氯丙嗪和羟丁酸钠）对反射稳定系统中出现的兴奋和抑制的预备（潜伏）条件的作用的特定特征。药理学分析表明，消化性条件活动的预备和触发机制主要具有胆碱能性质。M胆碱受体的阻断（通过阿米齐尔和阿美丁）会削弱或消除动态刻板模式中出现的预备条件，并在三到十天内干扰触发反应。苯海拉明对H胆碱受体的阻断会增强预备状态。
