Singh Baljit, Sharma D K, Gupta Atul
Department of Chemistry, Himachal Pradesh University, Shimla, H.P., India.
J Environ Sci Health B. 2009 Feb;44(2):113-22. doi: 10.1080/03601230802599019.
This paper describes the synthesis of starch and alginate beads as controlled release formulations. Different formulations of the fungicide, thiram, were prepared by using BaCl(2) and AlCl(3) as crosslinkers. The beads thus formed were characterized by FTIR and swelling studies. Formulation characteristics like entrapment efficiency, bead size, percentage equilibrium swelling have been evaluated. The release studies of the fungicide from the beads were carried out in vitro and in soil columns. The beads prepared with AlCl(3) have shown more swelling as well as the fungicide release in comparison to beads prepared with BaCl(2). From the soil column studies it was observed that the release of pesticide from the beads occurred in very controlled and sustained manner.
本文描述了作为控释制剂的淀粉和藻酸盐珠粒的合成。通过使用氯化钡(BaCl₂)和氯化铝(AlCl₃)作为交联剂制备了不同配方的杀菌剂福美双。通过傅里叶变换红外光谱(FTIR)和溶胀研究对由此形成的珠粒进行了表征。评估了诸如包封效率、珠粒大小、平衡溶胀百分比等制剂特性。在体外和土壤柱中进行了杀菌剂从珠粒中的释放研究。与用氯化钡制备的珠粒相比,用氯化铝制备的珠粒表现出更大的溶胀以及杀菌剂释放。从土壤柱研究中观察到,杀菌剂从珠粒中的释放以非常可控和持续的方式发生。