Dayananda G, Roopakala M S, Srinivasa R, Sharma Rajeev
Department of Physiology, M.S. Ramaiah Medical College and Hospital, Bangalore 560 054.
Indian J Physiol Pharmacol. 2008 Apr-Jun;52(2):183-8.
The totally blind individuals are often considered to be compensated for their visual loss by augmentation in the auditory and tactile perceptions as against the normal sighted individuals. The objective of the present work was to study the somatosensory evoked potentials (SEPs) after median nerve stimulation in the wrist of totally blind and normal sighted individuals. SEPs were recorded after median nerve stimulation in the wrist of 15 Braille reading totally blind females and compared with 15 age matched normal sighted females. Latency and amplitudes of SEPs (N9, N13, and N20) were measured and analyzed statistically. Amplitude of N20 SEP was significantly larger in the totally blind than in normal sighted individuals (P < 0.05). The amplitudes of N9 and N13 SEPs and the latencies of all SEPs showed no significant differences. The congenitally blind individuals have larger N20 amplitude, suggestive of greater somatosensory cortical representation than normal sighted individuals.
与视力正常的个体相比，全盲个体通常被认为通过增强听觉和触觉感知来补偿其视力丧失。本研究的目的是研究在全盲和视力正常个体的手腕处正中神经刺激后体感诱发电位（SEP）。在15名阅读盲文的全盲女性的手腕处进行正中神经刺激后记录SEP，并与15名年龄匹配的视力正常女性进行比较。测量SEP（N9、N13和N20）的潜伏期和波幅，并进行统计学分析。全盲个体中N20 SEP的波幅明显大于视力正常个体（P < 0.05）。N9和N13 SEP的波幅以及所有SEP的潜伏期均无显著差异。先天性盲人个体的N20波幅更大，表明其体感皮层代表区比视力正常个体更大。
