Chu N S
Department of Neurology, Chang Gung Medical College, Taipei, Taiwan.
Muscle Nerve. 1994 Mar;17(3):313-9. doi: 10.1002/mus.880170309.
To determine if retrograde conduction changes might occur long after injury of the most distal peripheral nerves, short-latency somatosensory evoked potentials (SEPs) to median or ulnar nerve stimulation at the wrist were studied in 10 subjects who had sustained traumatic digit amputation 4 months to 15 years previously. SEPs were recorded from Erb's point (N9), the cervical region (N13), and the contralateral scalp hand area (N20). While N9 latency was slightly delayed or not affected, the amplitude was either markedly reduced or undetectable. For N13 and N20 components, latency prolongation and amplitude reduction were mild to moderate, but the central conduction time (N13-N20) remained normal. The present data indicate that even the most distal nerve injury may have profound long-term retrograde effects on parental nerve function which are presumed mainly due to an axonopathy.
为了确定在最远端周围神经损伤很长时间后是否会发生逆行传导变化，我们对10名曾在4个月至15年前遭受外伤性手指截肢的受试者进行了研究，记录了在腕部刺激正中神经或尺神经时的短潜伏期体感诱发电位（SEP）。SEP记录点为Erb点（N9）、颈部区域（N13）和对侧头皮手部区域（N20）。虽然N9潜伏期稍有延迟或未受影响，但其波幅要么显著降低，要么无法检测到。对于N13和N20成分，潜伏期延长和波幅降低为轻度至中度，但中枢传导时间（N13 - N20）保持正常。目前的数据表明，即使是最远端的神经损伤也可能对母神经功能产生深远的长期逆行影响，这主要被认为是由于轴索性神经病所致。
