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S1P/S1P1 signaling stimulates cell migration and invasion in Wilms tumor.
Cancer Lett. 2009 Apr 18;276(2):171-9. doi: 10.1016/j.canlet.2008.11.025. Epub 2009 Jan 7.
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Sphingosine-1-phosphate promotes lymphangiogenesis by stimulating S1P1/Gi/PLC/Ca2+ signaling pathways.
Blood. 2008 Aug 15;112(4):1129-38. doi: 10.1182/blood-2007-11-125203. Epub 2008 Jun 9.
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Sphingosine-1-phosphate (S1P) displays sustained S1P1 receptor agonism and signaling through S1P lyase-dependent receptor recycling.
Cell Signal. 2014 Jul;26(7):1576-88. doi: 10.1016/j.cellsig.2014.03.029. Epub 2014 Apr 2.
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S1P/S1P2 signaling induces cyclooxygenase-2 expression in Wilms tumor.
J Urol. 2009 Mar;181(3):1347-52. doi: 10.1016/j.juro.2008.10.140. Epub 2009 Jan 20.

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Bioinformatics analysis and identification of genes and pathways involved in patients with Wilms tumor.
Transl Cancer Res. 2022 Aug;11(8):2843-2857. doi: 10.21037/tcr-22-1847.
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A Novel Radioimmune Tc-Labeled Tracer for Imaging Sphingosine 1-Phosphate Receptor 1 in Tumor Xenografts: An and Study.
Front Immunol. 2021 Aug 18;12:660842. doi: 10.3389/fimmu.2021.660842. eCollection 2021.
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Sphingolipid metabolism in the development and progression of cancer: one cancer's help is another's hindrance.
Mol Oncol. 2021 Dec;15(12):3256-3279. doi: 10.1002/1878-0261.13063. Epub 2021 Jul 29.
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Analysis of genes associated with prognosis of lung adenocarcinoma based on GEO and TCGA databases.
Medicine (Baltimore). 2020 May;99(19):e20183. doi: 10.1097/MD.0000000000020183.
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Roles of sphingosine-1-phosphate signaling in cancer.
Cancer Cell Int. 2019 Nov 14;19:295. doi: 10.1186/s12935-019-1014-8. eCollection 2019.

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1
Induction of vascular permeability by the sphingosine-1-phosphate receptor-2 (S1P2R) and its downstream effectors ROCK and PTEN.
Arterioscler Thromb Vasc Biol. 2007 Jun;27(6):1312-8. doi: 10.1161/ATVBAHA.107.143735. Epub 2007 Apr 12.
2
S1P stimulates chemotactic migration and invasion in OVCAR3 ovarian cancer cells.
Biochem Biophys Res Commun. 2007 Apr 27;356(1):239-44. doi: 10.1016/j.bbrc.2007.02.112. Epub 2007 Feb 28.
5
Oral fingolimod (FTY720) for relapsing multiple sclerosis.
N Engl J Med. 2006 Sep 14;355(11):1124-40. doi: 10.1056/NEJMoa052643.
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Antagonism of sphingosine-1-phosphate receptors by FTY720 inhibits angiogenesis and tumor vascularization.
Cancer Res. 2006 Jan 1;66(1):221-31. doi: 10.1158/0008-5472.CAN-05-2001.

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