Cimmino M A
Reumatismo. 2008 Oct-Dec;60(4):239-41. doi: 10.4081/reumatismo.2008.239.
In the last 15 years, new imaging techniques have changed the life of practicing rheumatologists in terms of both diagnostic approach and knowledge of disease mechanisms. Clinical symptoms, disease signs and the results of physical examination have been more closely related to their anatomical basis. In particular, magnetic resonance imaging allow diagnosis of disease in its early phase and its follow-up with a previously unknown sensitivity. Novel imaging studies have contributed to elucidate several pathogenetic mechanisms in musculoskeletal diseases, such as rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, polymyalgia rheumatica and osteoarthritis; allow evaluation of the real degree of joint inflammation, which is often uncoupled from clinical signs; and possibly reduce the need for large clinical trials. In conclusion, new imaging techniques and refinements of the established techniques have opened exciting perspectives in our understanding and treatment of many rheumatic diseases. Much attention should be paid to the training of new generations of rheumatologists in this field.
在过去15年里,新的成像技术在诊断方法和疾病机制认识方面改变了执业风湿病学家的工作方式。临床症状、体征和体格检查结果与其解剖学基础的联系更为紧密。特别是,磁共振成像能够以前所未有的灵敏度在疾病早期进行诊断并对其进行随访。新的成像研究有助于阐明肌肉骨骼疾病中的几种发病机制,如类风湿关节炎、银屑病关节炎、强直性脊柱炎、风湿性多肌痛和骨关节炎;能够评估关节炎症的实际程度,而这往往与临床体征不一致;并且可能减少大型临床试验的需求。总之,新的成像技术以及现有技术的改进为我们理解和治疗许多风湿性疾病开辟了令人兴奋的前景。在这一领域,应高度重视对新一代风湿病学家的培训。