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[伯基特淋巴瘤]

[Burkitt's lymphoma].

作者信息

Rathke W

出版信息

Fortschr Med. 1977 Mar 10;95(10):608-14.

PMID:191341
Abstract

The Burkitt's tumor is a neoplastic disease which occurs mostly in the tropics. Sporadic cases however are distributed all over the world. This undifferentiated lymphosarcoma predominates in children. Extralymphnodal in origin, quick growth and lack of pain are very characteristic signs. Unattended most of the patients die within a few months. Cytostatic treatment in connection with x-ray therapy and surgical proceedings show some results. The Epstein-Barr-virus is incriminated to play a causative role in the pathogenesis of Burkitt's lymphoma. But the experimental proof of its oncogenic activity in human beings has not yet been demonstrated. The problem of an active immunization is to be controlled.

摘要

伯基特氏瘤是一种主要发生在热带地区的肿瘤性疾病。不过,散发病例在世界各地均有分布。这种未分化的淋巴肉瘤在儿童中占主导。其起源于淋巴结外,生长迅速且无痛是非常典型的特征。多数患者若未得到治疗,会在数月内死亡。细胞抑制治疗结合X射线疗法和外科手术有一定效果。爱泼斯坦 - 巴尔病毒被认为在伯基特淋巴瘤的发病机制中起致病作用。但其在人类中的致癌活性的实验证据尚未得到证实。主动免疫的问题有待研究。

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