急性白血病伴谱系不一致病例中的13号染色体长臂三体
Trisomy 13q in a case of acute leukemia with lineage inconsistency.
作者信息
Comenzo R, Roth D, Desforges J F, Berkman E M
机构信息
Department of Medicine, New England Medical Center Hospital, Boston, MA 02111.
出版信息
Cancer Genet Cytogenet. 1991 Aug;55(1):107-11. doi: 10.1016/0165-4608(91)90243-n.
PMID:1913596
Abstract
A case of acute leukemia has two distinct immature blast lines, lineage inconsistency with CD 4 positivity, and trisomy 13q as the effective cytogenetic abnormality. This case represents another instance of trisomy 13 with acute leukemia developing in a more primitive pluripotent stem cell.
摘要
一例急性白血病患者具有两条不同的未成熟母细胞系，存在与CD4阳性不一致的谱系，且13号染色体长臂三体是有效的细胞遗传学异常。该病例代表了另一例13号染色体三体伴急性白血病在更原始的多能干细胞中发生的情况。
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