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死产的长期心理社会后遗症:巢式病例对照队列研究的第二阶段

Long-term psychosocial sequelae of stillbirth: phase II of a nested case-control cohort study.

作者信息

Turton Penelope, Evans Chris, Hughes Patricia

机构信息

Department of Mental Health, St. George's University of London, Cranmer Terrace, London, UK.

出版信息

Arch Womens Ment Health. 2009 Feb;12(1):35-41. doi: 10.1007/s00737-008-0040-7. Epub 2009 Jan 10.

Abstract

Stillbirth is associated with increased psychological morbidity in the subsequent pregnancy and puerperium. This study aimed to assess longer-term psychological and social outcomes of stillbirth and to identify factors associated with adverse outcome. We conducted seven-year follow-up of a cohort of women who were initially assessed during and after a pregnancy subsequent to stillbirth, together with pair-matched controls. All women were living with a partner at baseline and none had live children. Measured outcomes at follow-up included depression, posttraumatic stress disorder (PTSD) and partnership breakdown. Comparison variables included social and psychological factors and, for the stillbirth group, factors relating to the lost pregnancy. There were no differences between groups in case level psychological morbidity, but significantly higher levels of PTSD symptoms persisted in stillbirth group mothers who had case level PTSD 7 years earlier. Stillbirth group mothers were more likely to have experienced subsequent partnership breakdown. In the stillbirth group such breakdown was associated with having held the stillborn infant and having had case-level PTSD. Interpretations and clinical implications of these findings are discussed.

摘要

死产与随后妊娠及产褥期心理发病率增加有关。本研究旨在评估死产的长期心理和社会结局,并确定与不良结局相关的因素。我们对一组在死产后的妊娠期间及产后最初接受评估的女性及其配对对照进行了为期七年的随访。所有女性在基线时均与伴侣共同生活,且均无存活子女。随访时测量的结局包括抑郁、创伤后应激障碍(PTSD)和伴侣关系破裂。比较变量包括社会和心理因素,对于死产组,还包括与失去妊娠相关的因素。两组在病例水平的心理发病率方面无差异,但7年前患有病例水平PTSD的死产组母亲中,PTSD症状持续存在的水平显著更高。死产组母亲更有可能经历随后的伴侣关系破裂。在死产组中,这种破裂与抱过死产婴儿以及患有病例水平的PTSD有关。讨论了这些发现的解释和临床意义。

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