Sanchez Olivier
Université Paris-Descartes, faculté de médecine, service de pneumologie et soins intensifs, Hôpital européen Georges-Pompidou, AP-HP, 75908 Paris Cedex 15, France.
Rev Prat. 2008 Nov 30;58(18):2025-9.
Chronic thromboembolic pulmonary hypertension is characterized by the persistence of obstructive thromboemboli and pulmonary vascular remodelling in the open pulmonary arteries. The consequence is an increase in pulmonary vascular resistance and progressive right heart failure. Diagnosis is based on echocardiography, right heart catheterisation and ventilation-perfusion lung scan. Spiral CT and pulmonary angiography are required to assess operability. Pulmonary endarterectomy represents the treatment of choice. Antiproliferative treatments represent alternatives in the most severe and/or non operable patients.
慢性血栓栓塞性肺动脉高压的特征是在开放的肺动脉中存在持续性阻塞性血栓栓子和肺血管重塑。其结果是肺血管阻力增加和进行性右心衰竭。诊断基于超声心动图、右心导管检查和通气-灌注肺扫描。评估手术可行性需要螺旋CT和肺血管造影。肺动脉内膜剥脱术是首选治疗方法。抗增殖治疗是最严重和/或无法手术的患者的替代治疗方法。