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胚胎鸡皮肤外植体培养基中胶原酶与低分子量抑制剂的复合物。

A complex of collagenase with low molecular weight inhibitors in the culture medium of embryonic chick skin explants.

作者信息

Shinkai H, Kawamoto T, Hori H, Nagai Y

出版信息

J Biochem. 1977 Jan;81(1):261-3. doi: 10.1093/oxfordjournals.jbchem.a131444.

Abstract

Collagenase inhibitors with molecular weights of about 6,000 and 12,000 were isolated from latent chick skin collagenase treated with 3 M NaI and from the culture medium of embryonic skin explants. It is suggested that these inhibitors, which are possibly derived from connective tissue macromolecule metabolites, are candidates for regulating factors of collagenase activity in vivo.

摘要

从用3M碘化钠处理的潜伏性鸡皮肤胶原酶以及胚胎皮肤外植体的培养基中分离出分子量约为6000和12000的胶原酶抑制剂。有人提出,这些可能源自结缔组织大分子代谢产物的抑制剂是体内胶原酶活性调节因子的候选者。

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