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帕森奇-特纳综合征揭示莱姆病螺旋体病。

Parsonage-Turner syndrome revealing Lyme borreliosis.

作者信息

Wendling Daniel, Sevrin Philippe, Bouchaud-Chabot Agnès, Chabroux Aline, Toussirot Eric, Bardin Thomas, Michel Fabrice

机构信息

Service de Rhumatologie, CHU Jean Minjoz, et EA 3186 Agents Pathogènes et Inflammation Université de Franche-Comté, Boulevard Fleming, 25030 Besançon, France.

出版信息

Joint Bone Spine. 2009 Mar;76(2):202-4. doi: 10.1016/j.jbspin.2008.07.013. Epub 2009 Jan 14.

Abstract

Parsonage-Turner syndrome, also known as acute brachial neuritis or neuralgic amyotrophy, can be caused by various infectious agents. We report on four patients who experienced Parsonage-Turner syndrome as the first manifestation of Lyme disease. The clinical picture was typical, with acute shoulder pain followed rapidly by weakness and wasting of the shoulder girdle muscles. Electrophysiological testing showed denervation. A single patient reported erythema chronicum migrans after a tick bite. Examination of the cerebrospinal fluid showed lymphocytosis and protein elevation in 3 patients. Serological tests for Lyme disease were positive in the serum in all 4 patients and in the cerebrospinal fluid in 2 patients. Antibiotic therapy ensured a favorable outcome in all 4 cases. Two patients achieved a full recovery within 6 months. Parsonage-Turner syndrome should be added to the list of manifestations of neuroborreliosis. Serological tests for Lyme disease should be performed routinely in patients with Parsonage-Turner syndrome.

摘要

帕森奇-特纳综合征,也称为急性臂丛神经炎或神经性肌萎缩,可由多种感染因子引起。我们报告了4例以帕森奇-特纳综合征为莱姆病首发表现的患者。临床表现典型,急性肩部疼痛后迅速出现肩胛带肌肉无力和萎缩。电生理检查显示失神经支配。1例患者报告蜱叮咬后出现慢性游走性红斑。3例患者脑脊液检查显示淋巴细胞增多和蛋白升高。所有4例患者血清莱姆病血清学检测均为阳性,2例患者脑脊液检测为阳性。抗生素治疗使所有4例患者均取得良好疗效。2例患者在6个月内完全康复。帕森奇-特纳综合征应列入神经型莱姆病的表现清单。对于帕森奇-特纳综合征患者,应常规进行莱姆病血清学检测。

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