Facultés de Médecine Dentaire et de Médecine, Université de Montréal, CP 6128, Succursale Centre-ville, Montréal, Que., Canada.
Sleep Med. 2009 Aug;10(7):713-6. doi: 10.1016/j.sleep.2008.07.015. Epub 2009 Jan 14.
Sleep complaints (e.g., frequent awakenings, nightmares), headaches and mood alterations (e.g., feeling depressed, irritable) can appear following a mild traumatic brain injury (MTBI). The objective of this retrospective study was to assess the relationships between the above symptoms. Our hypothesis was that sleep complaints might be among the risk factors for the development of headaches and mood alterations.
The consecutive charts of 443 patients (68.2% males vs. 31.8% female; mean age of 46.9 years) diagnosed with MTBI were reviewed for past medical history and above symptoms using the Rivermead post-concussion symptom assessment questionnaire and self-report. Data were retrieved in 2 time courses: 10 days and 6 weeks.
For the 2 time courses, the prevalence of subjective sleep complaints were 13.3% and 33.5%; headaches 46.8% and 39.3%; feeling depressed 9.5% and 20.4%; and feeling irritable 5.6% and 20.2%, respectively. Reports of sleep complaints at 6 weeks were 2.9 times (p=0.004) more likely if such a symptom was reported at 10 days. Moreover, the presence of sleep complaints at 10 days is associated with concomitant headaches, depressive symptoms, and feeling irritable by 2.3, 9.9, and 12.2 times (p=0.0001 and 0.014); and by 2.9, 6.3, and 4.8 times (p=0.0001) at 6 weeks, respectively.
Our results suggest that patients afflicted with sleep complaints are more likely to suffer from concomitant headaches, depressive symptoms, and irritability.
睡眠问题（例如频繁觉醒、噩梦）、头痛和情绪改变（例如感到抑郁、易怒）可能会在轻度创伤性脑损伤（MTBI）后出现。本回顾性研究的目的是评估上述症状之间的关系。我们的假设是，睡眠问题可能是头痛和情绪改变发展的危险因素之一。
对 443 例（68.2%男性，31.8%女性；平均年龄 46.9 岁）MTBI 患者的连续病历进行了回顾，使用 Rivermead 脑震荡后症状评估问卷和自我报告评估了过去的病史和上述症状。数据在两个时间点检索：10 天和 6 周。
在这两个时间点，主观睡眠问题的患病率分别为 13.3%和 33.5%；头痛为 46.8%和 39.3%；感到抑郁为 9.5%和 20.4%；感到易怒为 5.6%和 20.2%。在 6 周时报告有睡眠问题的可能性是在 10 天时报告该症状的 2.9 倍（p=0.004）。此外，10 天时存在睡眠问题与同时存在头痛、抑郁症状和易怒分别相关 2.3 倍、9.9 倍和 12.2 倍（p=0.0001 和 0.014）；在 6 周时，分别相关 2.9 倍、6.3 倍和 4.8 倍（p=0.0001）。
我们的研究结果表明，患有睡眠问题的患者更有可能同时患有头痛、抑郁症状和易怒。
