Yu S D, Chen M Y, Johnson A J
Indiana University School of Medicine, Indianapolis, IN, USA.
AJNR Am J Neuroradiol. 2009 Mar;30(3):512-5. doi: 10.3174/ajnr.A1420. Epub 2009 Jan 15.
To minimize diagnostic confusion, a CSF specimen should be free from traumatically introduced red blood cells (RBCs). The purpose of this research is to determine if patient age, sex, gauge of the lumbar puncture (LP) needle, or the level of LP is associated with an increased risk for traumatic fluoroscopy-guided LP.
Data were collected retrospectively for consecutive male and female patients of all ages (n = 756) who underwent a fluoroscopy-guided LP for a 2-year period. We defined traumatic LP as a CSF sample with an RBC count more than 500 cells/mm(3) without xanthochromia.
Rate of traumatic LP was 13.3%. The rate of traumatic LP at the L4-L5 level (19%) was significantly higher than at the L2-L3 (9%) or L3-L4 level (10%). Patients older than 80 years had higher traumatic LP rates (25.9%) compared with patients between ages 11 and 80 years (12.4%). Sex and gauge of the spinal needle were not associated with increased rate of traumatic LP. Patients younger than 1 year had failed LP rate of 58.8% compared with 3.2% failure rate in older patients.
Fluoroscopy-guided LP at the L4-L5 level is associated with nearly twice the risk for traumatic puncture compared with the L2-L3 or L3-L4 level. Rates of traumatic result are twice as high in adults older than 80 years compared with younger patients. Failure rates for fluoroscopy-guided LP are low except in children younger than 1 year, in whom failure occurs in most cases.
为尽量减少诊断混淆,脑脊液(CSF)标本应不含因穿刺创伤引入的红细胞(RBCs)。本研究的目的是确定患者年龄、性别、腰椎穿刺(LP)针的规格或LP的部位是否与荧光透视引导下LP导致创伤风险增加相关。
回顾性收集连续两年接受荧光透视引导下LP的所有年龄段男性和女性患者(n = 756)的数据。我们将创伤性LP定义为脑脊液样本中红细胞计数超过500个细胞/mm³且无黄变现象。
创伤性LP的发生率为13.3%。L4 - L5水平的创伤性LP发生率(19%)显著高于L2 - L3(9%)或L3 - L4水平(10%)。80岁以上患者的创伤性LP发生率(25.9%)高于11至80岁患者(12.4%)。性别和脊髓穿刺针的规格与创伤性LP发生率增加无关。1岁以下患者的LP失败率为58.8%,而老年患者的失败率为3.2%。
与L2 - L3或L3 - L4水平相比,L4 - L5水平的荧光透视引导下LP导致创伤性穿刺的风险几乎高出一倍。80岁以上成年人的创伤性结果发生率是年轻患者的两倍。荧光透视引导下LP的失败率较低,1岁以下儿童除外,该年龄段大多数情况下会出现失败。