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类鼻疽与肺结核:颈部脓肿中的双重病原体

Melioidosis and tuberculosis: dual pathogens in a neck abscess.

作者信息

Shenoy V, Kamath M P, Hegde M C, D'Souza T, Mammen S S

机构信息

Department of ENT and Head and Neck Surgery, Kasturba Medical College, Mangalore, Karnataka State, India.

出版信息

J Laryngol Otol. 2009 Nov;123(11):1285-7. doi: 10.1017/S0022215109004460. Epub 2009 Jan 21.

DOI:10.1017/S0022215109004460
PMID:19154649
Abstract

INTRODUCTION

Melioidosis is an infectious disease caused by a saprophytic bacterium, Burkholderia pseudomallei. It is endemic to Southeast Asia and Northern Australia. It may manifest as a pulmonary lesion, osteomyelitis, abscesses in soft tissue and various organs, or as septicaemia.

CASE REPORT

We report a case of a 40-year-old, diabetic man who presented with a neck lump resulting from super-infection of a tuberculosis cavity with B pseudomallei. The patient was successfully managed by drainage along with meticulous excision of the capsule and prolonged antibiotic and anti-tubercular treatment.

DISCUSSION

Melioidosis may be confused diagnostically with tuberculosis, as both diseases are endemic in the same regions. Our patient was unfortunate to suffer from both endemic diseases simultaneously, perhaps representing the first such case in the world literature.

CONCLUSION

Increased awareness of melioidosis is important as, although the organism is easy to culture, it may be dismissed as a contaminant.

摘要

引言

类鼻疽是一种由腐生菌伯克霍尔德菌引起的传染病。它在东南亚和澳大利亚北部地区流行。它可能表现为肺部病变、骨髓炎、软组织和各种器官的脓肿,或败血症。

病例报告

我们报告一例40岁糖尿病男性患者,其颈部肿块是由结核空洞被伯克霍尔德菌超级感染所致。通过引流、仔细切除包膜以及延长抗生素和抗结核治疗,该患者得到了成功治疗。

讨论

类鼻疽在诊断上可能会与结核病混淆,因为这两种疾病在相同地区流行。我们的患者不幸同时患有这两种地方病,这可能是世界文献中首例此类病例。

结论

提高对类鼻疽的认识很重要,因为尽管该病菌易于培养,但它可能会被当作污染物而被忽视。

相似文献

1
Melioidosis and tuberculosis: dual pathogens in a neck abscess.类鼻疽与肺结核:颈部脓肿中的双重病原体
J Laryngol Otol. 2009 Nov;123(11):1285-7. doi: 10.1017/S0022215109004460. Epub 2009 Jan 21.
2
Melioidosis: an uncommon cause of neck abscess.类鼻疽:颈部脓肿的罕见病因。
Am J Otolaryngol. 2008 Jan-Feb;29(1):72-4. doi: 10.1016/j.amjoto.2007.02.004.
3
Burkholderia pseudomallei: abscess in an unusual site.类鼻疽伯克霍尔德菌:罕见部位的脓肿
J Postgrad Med. 2002 Apr-Jun;48(2):124-6.
4
[Melioidosis: the importance of a detailed medical history, including recent travels].类鼻疽:详细病史的重要性,包括近期旅行史
Ned Tijdschr Geneeskd. 2010;154:A279.
5
Disseminated septicaemic melioidosis: an unusual presentation of masticator space infection.播散性败血症型类鼻疽:咀嚼肌间隙感染的一种罕见表现。
J Laryngol Otol. 2003 May;117(5):417-8. doi: 10.1258/002221503321626528.
6
Melioidosis; the remarkable imitator: recent perspectives.类鼻疽;卓越的模仿者:近期观点
J Assoc Physicians India. 2004 May;52:417-20.
7
Diabetic ketoacidosis and melioidosis in a child.一名儿童的糖尿病酮症酸中毒和类鼻疽病
J Med Assoc Thai. 1997 Oct;80(10):671-4.
8
Melioidosis masquerading as enteric fever.伪装成伤寒的类鼻疽
Trans R Soc Trop Med Hyg. 2008 Dec;102 Suppl 1:S117-8. doi: 10.1016/S0035-9203(08)70027-0.
9
Cutaneous melioidosis.皮肤类鼻疽
J Eur Acad Dermatol Venereol. 2006 Nov;20(10):1322-4. doi: 10.1111/j.1468-3083.2006.01785.x.
10
Tuberculosis mimicked by melioidosis.类鼻疽伪装的结核病。
Int J Tuberc Lung Dis. 2008 Oct;12(10):1209-15.

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Front Cell Infect Microbiol. 2021 May 28;11:654745. doi: 10.3389/fcimb.2021.654745. eCollection 2021.
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Melioidosis of the Head and Neck: A Case Series from Eastern India.头颈部类鼻疽:来自印度东部的病例系列
Infect Dis Rep. 2020 Oct 29;12(3):36-45. doi: 10.3390/idr12030011.
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Tuberculosis and Melioidosis at Distinct Sites Occurring Simultaneously.不同部位同时发生的肺结核和类鼻疽病。
Case Rep Infect Dis. 2020 Jan 3;2020:9818129. doi: 10.1155/2020/9818129. eCollection 2020.
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Cervical abscesses due to co-infection with Burkholderia pseudomallei, Salmonella enterica serovar Stanley and Mycobacterium tuberculosis in a patient with diabetes mellitus.一名糖尿病患者因同时感染伯克霍尔德菌、肠炎沙门氏菌斯坦利血清型和结核分枝杆菌而发生颈部脓肿。
BMC Infect Dis. 2013 Nov 9;13:527. doi: 10.1186/1471-2334-13-527.