Kastenbaum Hannah A, McPherson Elizabeth W, Murdoch Geoffrey H, Ozolek John A
Department of Pathology, Division of Pediatric Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Pediatr Dev Pathol. 2009 Sep-Oct;12(5):374-82. doi: 10.2350/08-11-0555.1.
Conjoined twinning is a rare form of twinning, in which 2 bodies are attached, and is classified according to the anatomic place of attachment. An extremely rare form of conjoined twinning is janiceps conjoined twinning, in which 2 faces are attached but oriented in opposite directions. In this report, we present an unusual and difficult-to-classify case of conjoined male twins with partial duplication of craniofacial, upper oropharyngeal, and cardiac organs. We believe this to be one of the few reported cases of janiceps asymmetrus. We describe in detail the gross and microscopic pathology and offer some insights into the possible embryogenesis and distinction from the other rare form of conjoined twinning with facial duplication, diprosopus.
联体双胎是一种罕见的双胎形式,其中两个身体相连,并根据连接的解剖部位进行分类。一种极其罕见的联体双胎形式是双面联体双胎,即两个面部相连但方向相反。在本报告中,我们呈现了一例不寻常且难以分类的联体男性双胞胎病例,其颅面、上咽和心脏器官部分重复。我们认为这是少数报道的不对称双面联体双胎病例之一。我们详细描述了大体和微观病理学,并对可能的胚胎发生以及与另一种罕见的面部重复联体双胎——双面畸形的区别提供了一些见解。