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具有极端不对称性的Janiceps联体双胎:伴有完整尸检和组织病理学发现的病例报告

Janiceps conjoined twins with extreme asymmetry: case report with complete autopsy and histopathologic findings.

作者信息

Kastenbaum Hannah A, McPherson Elizabeth W, Murdoch Geoffrey H, Ozolek John A

机构信息

Department of Pathology, Division of Pediatric Pathology, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

出版信息

Pediatr Dev Pathol. 2009 Sep-Oct;12(5):374-82. doi: 10.2350/08-11-0555.1.

DOI:10.2350/08-11-0555.1
PMID:19159129
Abstract

Conjoined twinning is a rare form of twinning, in which 2 bodies are attached, and is classified according to the anatomic place of attachment. An extremely rare form of conjoined twinning is janiceps conjoined twinning, in which 2 faces are attached but oriented in opposite directions. In this report, we present an unusual and difficult-to-classify case of conjoined male twins with partial duplication of craniofacial, upper oropharyngeal, and cardiac organs. We believe this to be one of the few reported cases of janiceps asymmetrus. We describe in detail the gross and microscopic pathology and offer some insights into the possible embryogenesis and distinction from the other rare form of conjoined twinning with facial duplication, diprosopus.

摘要

联体双胎是一种罕见的双胎形式,其中两个身体相连,并根据连接的解剖部位进行分类。一种极其罕见的联体双胎形式是双面联体双胎,即两个面部相连但方向相反。在本报告中,我们呈现了一例不寻常且难以分类的联体男性双胞胎病例,其颅面、上咽和心脏器官部分重复。我们认为这是少数报道的不对称双面联体双胎病例之一。我们详细描述了大体和微观病理学,并对可能的胚胎发生以及与另一种罕见的面部重复联体双胎——双面畸形的区别提供了一些见解。

相似文献

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Janiceps conjoined twins with extreme asymmetry: case report with complete autopsy and histopathologic findings.具有极端不对称性的Janiceps联体双胎:伴有完整尸检和组织病理学发现的病例报告
Pediatr Dev Pathol. 2009 Sep-Oct;12(5):374-82. doi: 10.2350/08-11-0555.1.
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Diprosopus conjoined twins: radiologic, autoptic, and histologic study of a case.双面联体双胎:1例病例的放射学、尸检及组织学研究
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Monocephalus diprosopus, a rare form of conjoined twins, and associated congenital anomalies.单头双面联体双胎,一种罕见的联体双胎形式及相关先天性异常。
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引用本文的文献

1
Diprosopus: A Rare Case of Craniofacial Duplication and a Systematic Review of the Literature.双面畸胎:一种罕见的颅面重复畸形病例,并进行系统文献复习。
Genes (Basel). 2023 Aug 31;14(9):1745. doi: 10.3390/genes14091745.
2
Brain malformations in diprosopia observed in clinical cases, museum specimens and artistic representations.双头畸胎病例、博物馆标本和艺术表现中观察到的脑畸形。
Orphanet J Rare Dis. 2023 Mar 16;18(1):57. doi: 10.1186/s13023-023-02617-5.
3
Conjoined twins and conjoined triplets: At the heart of the matter.联体双胞胎和联体三胞胎:问题的核心。
Birth Defects Res. 2022 Jul 15;114(12):596-610. doi: 10.1002/bdr2.2066. Epub 2022 Jun 29.