Qu Xin-kai, Fang Wei-yi, Ye Jian-ding, Chen Qun-hui, Guan Shao-feng, Jiao Jing
Department of Cardiology, Shanghai Chest Hospital, Shang Jiaotong University, Shanghai 200030, China.
Zhonghua Yi Xue Za Zhi. 2008 Dec 16;88(46):3268-71.
To instigate the values of 64 row spiral CT in pre-operative assessment of the occlusion and intra-operative guidance in percutaneous coronary intervention for chronic total occlusion (CTO) in coronary heart disease.
Fifteen coronary disease patients planned to receive percutaneous coronary intervention underwent 64-row spiral CT-coronary angiography and coronary angiography (CAG). The diagnostic effects of these 2 techniques were compared.
Seventeen CTO lesions were confirmed. MSCT succeeded to show the lengths of the 17 CTO lesions with a calcification identification rate of 76.4%, significantly higher than that of the CAG (41.5%). By cross-section examination, MSCT succeeded to detect the occlusion degree of the calcified lesions, and showed that 3 CTO lesions were occluded at a rate < 50%, and 10 lesions at a rate > or = 50%. Twelve complete occlusion lesions in 11 patients underwent PCT, success was seen in 6 of which and failure in the other 6. Univariate analysis showed that the length of lesion, branching at the proximal site, formation of bridging lateral branch, form of occlusion end, and calcification were all not significantly related to the success or failure of intervention. The percentage of the calcification area > or = 50% in the intervention failure group was 83.3%, significantly higher than that in the intervention success group (16.7%, P = 0.05). 3-D images of coronary artery could be obtained by MSCT to show all the complete occlusive lesions.
64-MSCT demonstrates a remarkable ability to identify silicified lesions, can re-establish 3-D images of coronary artery, and effectively guide the intervention therapy.
探讨64排螺旋CT在冠心病慢性完全闭塞(CTO)病变经皮冠状动脉介入治疗术前评估及术中指导中的应用价值。
对15例拟行冠状动脉介入治疗的冠心病患者行64排螺旋CT冠状动脉造影及常规冠状动脉造影(CAG),比较两种检查方法的诊断效果。
共确诊17处CTO病变。MSCT成功显示了17处CTO病变的长度,钙化识别率为76.4%,明显高于CAG(41.5%)。通过横断面观察,MSCT能探测钙化病变的闭塞程度,显示3处CTO病变闭塞率<50%,10处病变闭塞率≥50%。11例患者的12处完全闭塞病变行PCT,其中6例成功,6例失败。单因素分析显示,病变长度、近端分支、桥侧支形成、闭塞端形态及钙化等与介入成败均无明显相关性。介入失败组钙化面积≥50%者占83.3%,明显高于介入成功组(16.7%,P = 0.05)。MSCT可获得冠状动脉三维图像,显示所有完全闭塞病变。
64-MSCT对钙化病变有显著的识别能力,能重建冠状动脉三维图像,有效指导介入治疗。