用于清除生物沉积物的磁性微致动器的功能评估：一项体外研究。
Functional evaluation of magnetic microactuators for removing biological accumulation: an in vitro study.
作者信息
Lee Selene A, Pinney James R, Khialeeva Elvira, Bergsneider Marvin, Judy Jack W
机构信息
NeuroEngineering Training Program, University of California, Los Angeles, Los Angeles, CA 90095 USA.
出版信息
Annu Int Conf IEEE Eng Med Biol Soc. 2008;2008:947-50. doi: 10.1109/IEMBS.2008.4649311.
Here we demonstrate the functional capability of microfabricated magnetic actuators in clearing biological accumulation on a model catheter pore. Cell-clearing performance was quantitatively measured by comparing the effect of actuation on the cell density of aggressively growing adherent murine cells. Devices were actuated at a frequency of 100 Hz and a magnetic field of 17.8 kA/m for 30, 45, or 60 min. On average, microactuators removed 37.4% of the adherent cells. The results also revealed that the cell-clearing capability of the microactuator increased as a function of the actuation duration and angle of deflection.
在此，我们展示了微纳加工磁致动器在清除模型导管孔隙中生物堆积物方面的功能能力。通过比较致动对快速生长的贴壁小鼠细胞密度的影响，对细胞清除性能进行了定量测量。在100 Hz的频率和17.8 kA/m的磁场下对装置进行30、45或60分钟的致动。平均而言，微致动器清除了37.4%的贴壁细胞。结果还表明，微致动器的细胞清除能力随致动持续时间和偏转角的增加而增强。
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