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用于银屑病面积和严重程度指数(PASI)评分的银屑病红斑客观评估。

Objective assessment of psoriasis erythema for PASI scoring.

作者信息

Ahmad Fadzil M H, Ihtatho Dani, Affandi Azura Mohd, Hussein S H

机构信息

Department of Electrical and Electronics Engineering, Universiti Teknologi PETRONAS, Bandar Sri Iskandar, 31750 Tronoh, Perak Darul Ridzuan, Malaysia.

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2008;2008:4070-3. doi: 10.1109/IEMBS.2008.4650103.

Abstract

Skin colour is vital information in dermatological diagnosis. It reflects pathological condition beneath the skin and commonly being used to indicate the extent of a disease. Psoriasis is a skin disease which is indicated by the appearance of red plaques. Although there is no cure for psoriasis, there are many treatment modalities to help control the disease. To evaluate treatment efficacy, PASI (Psoriasis Area and Severity Index) which is the current gold standard method is used to determine severity of psoriasis lesion. Erythema (redness) is one parameter in PASI. Commonly, the erythema is assessed visually, thus leading to subjective and inconsistent result. In this work, we proposed an objective assessment of psoriasis erythema for PASI scoring. The colour of psoriasis lesion is analyzed by DeltaL, Deltahue, and Deltachroma of CIELAB colour space. References of lesion with different scores are obtained from the selected lesions by two dermatologists. Results based on 38 lesions from 22 patients with various level of skin pigmentation show that PASI erythema score can be determined objectively and consistent with dermatology scoring.

摘要

皮肤颜色是皮肤病诊断中的重要信息。它反映了皮肤下的病理状况,并且通常用于指示疾病的程度。银屑病是一种以红色斑块出现为特征的皮肤病。虽然银屑病无法治愈,但有许多治疗方法可帮助控制病情。为了评估治疗效果,目前的金标准方法——银屑病面积和严重程度指数(PASI)被用于确定银屑病皮损的严重程度。红斑是PASI中的一个参数。通常,红斑通过视觉评估,从而导致主观且不一致的结果。在这项工作中,我们提出了一种用于PASI评分的银屑病红斑客观评估方法。通过CIELAB颜色空间的DeltaL、Deltahue和Deltachroma分析银屑病皮损的颜色。由两位皮肤科医生从选定的皮损中获取不同评分的皮损参考。基于22名不同皮肤色素沉着水平患者的38个皮损的结果表明,PASI红斑评分可以客观确定,并且与皮肤科评分一致。

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