Centro Studi Gruppo Italiano Studi Epidemiologici in Dermatologia and Department of Dermatology, Ospedali Riuniti, Largo Barozzi 1, 24100 Bergamo, Italy.
Clin Dermatol. 2010 Jan-Feb;28(1):67-72. doi: 10.1016/j.clindermatol.2009.03.001.
Instruments to measure and to monitor the severity of psoriasis over time are needed for research and for optimal patient care. Scoring psoriasis has moved from an earlier time when clinical categories were adopted without concern about their reliability; for example, from clearance to more recent semi-quantitative scores, such as the Psoriasis Area and Severity Index (PASI), that carry the allure of being objective and quantitative "hard" data but actually translate a subjective judgement into a number. The PASI score has never been standardized, and data on interrater and intrarater reliability are limited. Better clinimetrics of disease severity are needed. The next generation of instruments should reflect the major concern of patients and treating physicians relative to safe and effective long-term disease control for a lifelong condition.
为了研究和优化患者护理，需要有衡量和监测银屑病严重程度的工具。在过去，人们对其可靠性毫不关心，直接采用临床类别来对银屑病进行评分；而现在，情况已经有所改变，人们已经采用了更为先进的半定量评分，例如银屑病面积和严重程度指数（PASI），这些评分看似客观、定量的“硬”数据，但实际上是将主观判断转化为数字。PASI 评分从未标准化，有关评分者间和评分者内信度的数据也很有限。需要有更好的疾病严重程度临床衡量标准。下一代工具应反映患者和治疗医生对安全有效的长期疾病控制的主要关注，因为这是一种终身疾病。
