Andreev Grigory B, Budantseva Nina A, Tananaev Ivan G, Myasoedov Boris F
A. N. Frumkin Institute of Physical Chemistry and Electrochemistry of Russian Academy of Sciences, 31 Leninskiy pr., Moscow, 119991, Russia.
Inorg Chem. 2009 Feb 2;48(3):1232-5. doi: 10.1021/ic801882p.
New Np(V) complexes with imidazole, [NpO(2)(CH(3)COO)(Im)(2)(H(2)O)], [(NpO(2))(2)(C(2)O(4))(Im)(6)] x 5 Im x H(2)O, and [NpO(2)(NO(2))(Im)(4)], were synthesized. Their crystal structures were determined using X-ray single-crystal diffractometry. The crystal structures are confirmed by IR and UV-vis spectroscopic data. In all three complexes, neptunium coordinates the imidazole molecule through the nitrogen atom. These complexes are the first example of direct bonding of the imidazole molecule to the actinide atom. These results suggest that coordination of histidine residue in proteins or other imidazole-containing biologically important molecules could occur under usual biological conditions.
合成了新型的含咪唑的Np(V)配合物，即[NpO(2)(CH(3)COO)(Im)(2)(H(2)O)]、[(NpO(2))(2)(C(2)O(4))(Im)(6)]·5Im·H(2)O和[NpO(2)(NO(2))(Im)(4)]。利用X射线单晶衍射测定了它们的晶体结构。通过红外光谱和紫外可见光谱数据对晶体结构进行了确认。在所有这三种配合物中，镎通过氮原子与咪唑分子配位。这些配合物是咪唑分子与锕系原子直接键合的首个实例。这些结果表明，在通常的生物条件下，蛋白质中的组氨酸残基或其他含咪唑的具有生物学重要性的分子可能会发生配位作用。
