Breyer Michael J, Giordano Michael, Tinjum Banu, Getto Leila, Rhodes Nathan, Bollinger Melissa, Sierzenski Paul, O'Connor Robert E
Department of Emergency Medicine, Christiana Care Health System, Newark, Delaware 19718, USA.
J Emerg Med. 2010 Jul;39(1):65-9. doi: 10.1016/j.jemermed.2008.10.002. Epub 2009 Jan 26.
Gallbladder ultrasonography is a commonly performed test in the emergency department. It is unknown whether a non-fasting state alters the visualization of the gallbladder by emergency medicine (EM) residents.
We conducted this study to determine whether EM residents are able to visualize the gallbladder in volunteers who have recently consumed a fatty meal.
This study used a prospective, single-blinded, randomized controlled design. Initial scans were performed on fasting volunteers. A fatty meal was then consumed. Thirty minutes after eating, a different resident, who was unaware of whether the volunteer had eaten or fasted, performed a second scan. To control for operator bias, 10% of subjects remained fasting between scans. Student's paired-samples t-test, Pearson's chi-squared, and McNemar test were determined as appropriate.
A total of 92 scans from 46 volunteers were analyzed. EM residents were able to visualize the gallbladder in all 40 pre-prandial scans (100%) and all 40 post-prandial scans (100%). Gallbladder area as measured in the longitudinal axis decreased 20% from a mean baseline of 11.58 +/- 4.86 cm(2) (95% confidence interval [CI] 11.17-12.98) to 9.2 +/- 5.04 cm(2) (95% CI 7.74-10.66, p = 0.0009) after food intake. Total time to scan for the fasting volunteers (110.2 s, 95% CI 84.34-136) did not change significantly from non-fasting volunteers (129.7 s, 95% CI 110.29-149.01, p = 0.153).
EM residents are able to visualize the gallbladder in non-fasted healthy volunteers.
胆囊超声检查是急诊科常用的检查项目。目前尚不清楚非禁食状态是否会影响急诊医学(EM)住院医师对胆囊的观察。
我们开展这项研究以确定EM住院医师能否在近期进食过油腻食物的志愿者中观察到胆囊。
本研究采用前瞻性、单盲、随机对照设计。首先对禁食的志愿者进行扫描。然后让他们进食一顿油腻食物。进食30分钟后,由另一位不知道志愿者是进食还是禁食的住院医师进行第二次扫描。为控制操作者偏倚,10%的受试者在两次扫描之间保持禁食状态。根据情况采用学生配对样本t检验、Pearson卡方检验和McNemar检验。
共分析了46名志愿者的92次扫描结果。EM住院医师在所有40次餐前扫描(100%)和所有40次餐后扫描(100%)中均能观察到胆囊。沿纵轴测量的胆囊面积从平均基线11.58±4.86平方厘米(95%置信区间[CI]11.17 - 12.98)进食后降至9.2±5.04平方厘米(95%CI 7.74 - 10.66,p = 0.0009)。禁食志愿者的总扫描时间(110.2秒,95%CI 84.34 - 136)与非禁食志愿者(129.7秒,95%CI 110.29 - 149.01,p = 0.153)相比无显著变化。
EM住院医师能够在未禁食的健康志愿者中观察到胆囊。