Mogk M, Zmierczak H, Wiest R, Brückel M, Hatz H J, Helmke K
Städtisches Krankenhaus München-Bogenhausen, Akademisches Lehrkrankenhaus der TU München.
Immun Infekt. 1991 Jun;19(3):92-3.
Therapy with 7S-immunoglobulins in 8 patients with various connective tissue diseases led to a decrease of clinical disease activity. In vitro experiments showed that treatment induces change of B-cell function. Significant quantitative alteration of relative lymphocyte subpopulations did not occur. CRP, C3c, C4 and circulating immune complexes tended to normalization.
对8例患有各种结缔组织疾病的患者使用7S免疫球蛋白进行治疗,使临床疾病活动度降低。体外实验表明,该治疗可诱导B细胞功能发生变化。相对淋巴细胞亚群未出现明显的定量改变。CRP、C3c、C4和循环免疫复合物趋于正常化。