Garcia Carlos Alexandre de Amorim, Segundo Paulo de Souza, Garcia Filho Carlos Alexandre de Amorim, Garcia Ana Cláudia Medeiros de Amorim
Ophthalmology Department, Universidade Federal do Rio Grande do Norte - Natal (RN) - Brazil.
Arq Bras Oftalmol. 2008 Nov-Dec;71(6):890-3. doi: 10.1590/s0004-27492008000600026.
Choroidal neovascularization is a very rare complication in intermediate uveitis. A 27-year-old female patient diagnosed with intermediate uveitis two years ago. She presented with 20/200 visual acuity, snowballs, snowbanks, and macular cystoid edema in the right eye observed by fluorescein and optical coherence tomography (OCT). Photocoagulation was performed in the inferior peripheral retina in both eyes. The patient refused to undergo the prescribed clinical treatment. She returned twelve months later presenting with count fingers visual acuity, dry retina and subretinal macular pigmented granuloma observed on OCT. A 15-year-old female patient with decreased visual acuity of 20/400 in the right eye for eight days. She presented with bilateral vasculitis and papilitis, in the right eye, hemorrhage and extramacular subretinal neovascular membrane were observed on fluorescein and OCT. She was treated with 40 mg prednisone and intravitreous injection of 1.25 mg bevacizumab. Five months later she presented with 20/50 visual acuity, and extramacular granuloma observed on OCT. The formation of subretinal granuloma in intermediate uveitis is a possibility when complicated by subretinal neovascular membrane.
脉络膜新生血管形成是中间葡萄膜炎中一种非常罕见的并发症。一名27岁女性患者两年前被诊断为中间葡萄膜炎。她右眼视力为20/200,通过荧光素眼底血管造影和光学相干断层扫描(OCT)观察到有雪球样病变、雪堤样病变和黄斑囊样水肿。双眼的周边视网膜下方进行了光凝治疗。该患者拒绝接受规定的临床治疗。十二个月后她复诊时视力为指数,视网膜干燥,OCT显示黄斑下有色素性肉芽肿。一名15岁女性患者右眼视力下降至20/400已有八天。她表现为双侧血管炎和视乳头炎,右眼荧光素眼底血管造影和OCT显示有出血和黄斑外视网膜下新生血管膜。她接受了40毫克泼尼松治疗及玻璃体内注射1.25毫克贝伐单抗。五个月后她的视力为20/50,OCT显示有黄斑外肉芽肿。中间葡萄膜炎合并视网膜下新生血管膜时有可能形成视网膜下肉芽肿。