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冠状动脉搭桥术后与健康相关的生活质量。一项随机对照家庭干预项目的影响。

Health-related quality of life after coronary artery bypass grafting. The impact of a randomised controlled home-based intervention program.

作者信息

Lie Irene, Arnesen Harald, Sandvik Leiv, Hamilton Glenys, Bunch Eli H

机构信息

Department of Nursing Research, Ullevål University Hospital, 0407, Oslo, Norway.

出版信息

Qual Life Res. 2009 Mar;18(2):201-7. doi: 10.1007/s11136-008-9438-y. Epub 2009 Jan 25.

Abstract

OBJECTIVE

The aim of this study was to evaluate the impact of a home based intervention program (HBIP) on health related quality of life (HRQoL) after coronary artery bypass grafting (CABG). To strengthen the clinical interpretation, HRQoL data were compared to the general population.

METHODS

In a randomised controlled trial (RCT), a total of 185 CABG patients (93 vs 92) completed the study. The intervention group received a HBIP 2 and 4 weeks after surgery. HRQoL was measured by the Seattle Angina Questionnaire (SAQ) and the Short Form 36 (SF-36) in both patient groups before surgery, at 6 weeks and 6 months after surgery.

RESULTS

Significant improvements were found in both groups for the majority of subscales of HRQoL at 6-week and 6-month follow-up. However, these improvements did not differ significantly between the groups. Compared to the general population, significant differences (P < 0.05) were found for the SF-36 subscales: role physical, role emotional and bodily pain.

CONCLUSIONS

HRQoL after CABG improved markedly over time, but no significant or clinically important differences were found when compared with controls. Thus, work to further develop and test the effect of a HBIP on HRQoL in patients undergoing rehabilitation following CABG is warranted.

摘要

目的

本研究旨在评估家庭干预项目(HBIP)对冠状动脉旁路移植术(CABG)后健康相关生活质量(HRQoL)的影响。为加强临床解读,将HRQoL数据与普通人群进行了比较。

方法

在一项随机对照试验(RCT)中,共有185例CABG患者(93例对92例)完成了研究。干预组在术后2周和4周接受了HBIP。在手术前、术后6周和6个月,两组患者均通过西雅图心绞痛问卷(SAQ)和简短健康调查问卷(SF-36)对HRQoL进行了测量。

结果

在6周和6个月的随访中,两组患者HRQoL的大多数子量表均有显著改善。然而,两组之间的这些改善并无显著差异。与普通人群相比,SF-36子量表在角色身体功能、角色情感功能和身体疼痛方面存在显著差异(P < 0.05)。

结论

CABG术后HRQoL随时间显著改善,但与对照组相比未发现显著或具有临床意义的差异。因此,有必要进一步开展工作,开发并测试HBIP对CABG术后康复患者HRQoL的影响。

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