Itabashi Kazuo, Horiuchi Takeshi, Kusuda Satoshi, Kabe Kazuhiko, Itani Yasufumi, Nakamura Takashi, Fujimura Masanori, Matsuo Masafumi
Department of Pediatrics, Showa University School of Medicine, 1-5-8 Hatanodai, Shinagawa-ku, Tokyo 142-8666, Japan.
Pediatrics. 2009 Feb;123(2):445-50. doi: 10.1542/peds.2008-0763.
Our goal was to investigate the neonatal mortality rate and the mortality rate during the NICU stay for extremely low birth weight infants born in Japan in 2005.
The Committee of Neonatal Medicine of the Japan Pediatric Society retrospectively surveyed the deaths of extremely low birth weight infants born and hospitalized between January 1 and December 31, 2005. From 297 institutions in Japan, data on 3065 extremely low birth weight infants, which represented 98.4% of those reported in the maternal and health statistics of Japan in 2005, were collected.
The neonatal mortality rate and the mortality rate during the NICU stay were 13.0% and 17.0%, respectively, which were lower than 17.7% and 21.5% in the survey in 2000. The neonatal mortality rates and the mortality rates during the NICU stay were 53.3% and 67.7% in the <400-g birth weight group (n = 62), 42.1% and 53.5% in the 400- to 499-g birth weight group (n = 159), 22.2% and 27.7% in the 500- to 599-g birth weight group (n = 387), 16.8% and 22.2% in the 600- to 699-g birth weight group (n = 537), 9.4% and 12.7% in the 700- to 799-g birth weight group (n = 574), 6.3% and 9.1% in the 800- to 899-g birth weight group (n = 649), and 3.9% and 5.3% in the 900- to 999-g birth weight group (n = 697), respectively. The factors involved in the deaths of extremely low birth weight infants included lower gestational age, lower birth weight, male gender, multiple birth, institutions in which <10 extremely low birth weight infants were admitted per year, and no prenatal maternal transfer.
The mortality rates of extremely low birth weight infants who were born in 2005 demonstrated definite improvement.
我们的目标是调查2005年在日本出生的极低出生体重儿的新生儿死亡率和新生儿重症监护病房（NICU）住院期间的死亡率。
日本儿科学会新生儿医学委员会对2005年1月1日至12月31日期间出生并住院的极低出生体重儿的死亡情况进行了回顾性调查。从日本的297家机构收集了3065例极低出生体重儿的数据，这些数据占2005年日本孕产妇和健康统计报告中极低出生体重儿的98.4%。
新生儿死亡率和NICU住院期间的死亡率分别为13.0%和17.0%，低于2000年调查中的17.7%和 21.5%。出生体重<400g组（n = 62）的新生儿死亡率和NICU住院期间的死亡率分别为53.3%和67.7%，出生体重400至499g组（n = 159）为42.1%和53.5%，出生体重500至599g组（n = 387）为22.2%和27.7%，出生体重600至699g组（n = 537）为16.8%和22.2%，出生体重700至799g组（n = 574）为9.4%和12.7%，出生体重800至899g组（n = 649）为6.3%和9.1%，出生体重900至999g组（n = 697）为3.9%和5.3%。极低出生体重儿死亡相关因素包括胎龄较小、出生体重较低、男性、多胎、每年收治极低出生体重儿<10例的机构以及产前未进行孕产妇转运。
2005年出生的极低出生体重儿的死亡率有了明显改善。
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