类似头颈部复发性鳞状细胞癌的软骨样化生

Chondroid metaplasia mimicking recurrent squamous cell carcinoma of the head and neck.

作者信息

Kohl Shane K, Simpson Roger J, Wisecarver James

机构信息

Department of Pathology and Microbiology, University of Nebraska Medical Center, Methodist Health System, 8303 Dodge St., Omaha, NE 68114, USA.

出版信息

Ear Nose Throat J. 2009 Jan;88(1):E4.

PMID:19172559

Abstract

A 65-year-old woman presented with a "sore bump" on her tongue. She had a history of squamous cell carcinoma of the head and neck that had been treated with surgery and radiotherapy 11 years earlier. The tongue lesion was excised, and pathologic examination identified a submucosal focus of benign-appearing cartilage. No evidence of dysplasia or malignancy was seen. She was diagnosed with chondroid metaplasia. Chondroid metaplasia involving the head and neck is rare. When it has occurred, it has been seen in both reactive and neoplastic settings. To our knowledge, this is the first reported case of a chondroid metaplasia of the tongue.

摘要

一名65岁女性因舌部出现“疼痛性肿块”前来就诊。她有头颈部鳞状细胞癌病史，11年前接受过手术和放疗。舌部病变被切除，病理检查发现一个外观良性的软骨黏膜下病灶。未见发育异常或恶性的证据。她被诊断为软骨化生。累及头颈部的软骨化生很罕见。当它发生时，可见于反应性和肿瘤性情况。据我们所知，这是首例舌部软骨化生的报道病例。