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1
Formation and function of the lytic NK-cell immunological synapse.
Nat Rev Immunol. 2008 Sep;8(9):713-25. doi: 10.1038/nri2381.
2
Measurement of Lytic Granule Convergence After Formation of an NK Cell Immunological Synapse.
Methods Mol Biol. 2017;1584:497-515. doi: 10.1007/978-1-4939-6881-7_31.
3
NK cell lytic granules are highly motile at the immunological synapse and require F-actin for post-degranulation persistence.
J Immunol. 2012 Nov 15;189(10):4870-80. doi: 10.4049/jimmunol.1201296. Epub 2012 Oct 12.
5
Cell biological steps and checkpoints in accessing NK cell cytotoxicity.
Immunol Cell Biol. 2014 Mar;92(3):245-55. doi: 10.1038/icb.2013.96. Epub 2014 Jan 21.
6
The lytic NK cell immunological synapse and sequential steps in its formation.
Adv Exp Med Biol. 2007;601:225-33. doi: 10.1007/978-0-387-72005-0_23.
7
Natural killer cell cytotoxicity: how do they pull the trigger?
Immunology. 2009 Sep;128(1):7-15. doi: 10.1111/j.1365-2567.2009.03123.x.
8
Analysis of the NK cell immunological synapse.
Methods Mol Biol. 2010;612:127-48. doi: 10.1007/978-1-60761-362-6_9.
9
Navigating barriers: the challenge of directed secretion at the natural killer cell lytic immunological synapse.
J Clin Immunol. 2010 May;30(3):358-63. doi: 10.1007/s10875-010-9372-y. Epub 2010 Feb 27.
10
Acute myeloid leukemia impairs natural killer cells through the formation of a deficient cytotoxic immunological synapse.
Eur J Immunol. 2014 Oct;44(10):3068-80. doi: 10.1002/eji.201444500. Epub 2014 Sep 4.

引用本文的文献

2
Natural Killer (NK) Cell Alloreactivity in Haploidentical Stem Cell Transplantation.
Cells. 2025 Jul 16;14(14):1091. doi: 10.3390/cells14141091.
3
Natural killer cell membrane manipulation for augmented immune synapse and anticancer efficacy.
Mater Today Bio. 2025 Jun 9;33:101965. doi: 10.1016/j.mtbio.2025.101965. eCollection 2025 Aug.
5
Neutralizing Antibodies: Role in Immune Response and Viral Vector Based Gene Therapy.
Int J Mol Sci. 2025 May 29;26(11):5224. doi: 10.3390/ijms26115224.
7
RAC2 inhibition enhances tumor sensitivity to NK cell-mediated cytotoxicity.
J Immunother Cancer. 2025 May 2;13(5):e010931. doi: 10.1136/jitc-2024-010931.
8
Molecular basis of β2 integrin activation by talin unveils subunit-specific mechanisms of integrin signaling.
Cell Rep. 2025 May 27;44(5):115607. doi: 10.1016/j.celrep.2025.115607. Epub 2025 Apr 29.
9
Selective requirement of glycosphingolipid synthesis for natural killer and cytotoxic T cells.
Cell. 2025 Jun 26;188(13):3497-3512.e16. doi: 10.1016/j.cell.2025.04.007. Epub 2025 Apr 29.
10
Single-chain variable fragment affinity tuning can optimize anti-AML CAR-NK cell functionality.
J Immunother Cancer. 2025 Feb 6;13(2):e010763. doi: 10.1136/jitc-2024-010763.

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1
Vesicle-associated membrane protein 7 (VAMP-7) is essential for target cell killing in a natural killer cell line.
Biochem Biophys Res Commun. 2008 Feb 15;366(3):617-23. doi: 10.1016/j.bbrc.2007.11.079. Epub 2007 Nov 26.
2
Immune synapse formation requires ZAP-70 recruitment by ezrin and CD43 removal by moesin.
J Cell Biol. 2007 Nov 19;179(4):733-46. doi: 10.1083/jcb.200707199.
3
NKp30 ligation induces rapid activation of the canonical NF-kappaB pathway in NK cells.
J Immunol. 2007 Dec 1;179(11):7385-96. doi: 10.4049/jimmunol.179.11.7385.
5
The trafficking of natural killer cells.
Immunol Rev. 2007 Dec;220(1):169-82. doi: 10.1111/j.1600-065X.2007.00563.x.
6
Phosphatidylinositol 3-kinase activation is required to form the NKG2D immunological synapse.
Mol Cell Biol. 2007 Dec;27(24):8583-99. doi: 10.1128/MCB.01477-07. Epub 2007 Oct 8.
7
Myosin IIA is required for cytolytic granule exocytosis in human NK cells.
J Exp Med. 2007 Oct 1;204(10):2285-91. doi: 10.1084/jem.20071143. Epub 2007 Sep 17.
8
Cutting edge: syntaxin 11 regulates lymphocyte-mediated secretion and cytotoxicity.
J Immunol. 2007 Sep 15;179(6):3397-401. doi: 10.4049/jimmunol.179.6.3397.
10
Membranous structures transfer cell surface proteins across NK cell immune synapses.
Traffic. 2007 Sep;8(9):1190-204. doi: 10.1111/j.1600-0854.2007.00603.x. Epub 2007 Jul 1.

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