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[肛门直肠莱什诺夫斯基-克罗恩病]

[Anorectal Leśniowski-Crohn's disease].

作者信息

Bielecki Krzysztof, Baczuk Lech

机构信息

Z Kliniki Chirurgii Ogólnej i Przewodu Pokarmowego, Centrum Medycznego Kształcenia Podyplomowego w Warszawie.

出版信息

Wiad Lek. 2008;61(7-9):177-82.

Abstract

UNLABELLED

Authors retrospectively reviewed results of surgical treatment of the patients with anorectal Leśniowski-Crohn's (LC) disease, operated in the Department of General and Gastroenterological Surgery in Warsaw.

MATERIAL AND METHODS

In years 1987-2007 we treated 110 patients with LC disease. The anorectal localization of lesions was noticed in 24 patients (13 women, 11 men, average age of fall--28 year), i.e. 21.8% of all patients. The operations performed in other hospitals were taken into account. Results were compared with literature data.

RESULTS

Anorectal lesions were the first signs of LC disease in 16/110 patients (14.5%), and there were most often: perianal fistulas (multiple) in 12, perianal abscesses in 2, and rectovaginal fistula in 2 patients. In the remaining 8 patients (7.3%), anorectal lesions emerged in later period of the disease, formerly placed in other part of digestive tract. The primary local surgical treatment (incision/excision offistulas, abscess drainage) was performed in 20/24 patients. Most frequent indications were: perianal fistulas--13, perianal abscesses--6, and rectovaginal fistula--1. Primary abdominal operations were performed in 4/24 patients: Hartman procedure in 2 patients with rectovaginal fistulas and in other 2 patients with severe colitis--subtotal colectomy and restorative proctocolectomy. The follow-up in 23/24 patients exceeded 5 years, only in 1 patient was 4 years. The surgical recurrences were noticed in 19/24 (79.1%) patients. Recurrences of fistulas were noticed in 11 patients, in addiction in 5 patients we noticed anal stenosis, in 3 rectal/sigmoidal stenosis and in 3 proctitis of the remaining rectal stump. Surgical recurrences of LC disease after 5, 10 and 15 years of observation were 18/23--78.2%, 14/15-93.3%, and 7/7--100% respectively. Two patients (8.3%) died from severe general complications of the disease. The primary local surgical treatment was sufficient only in 2 patients. In 18/22 patients 28 abdominal operations were carried out in later period of the disease. In all 24 patients we performed 46 extended abdominal operations. In result of them 13/24 patients have definitive and 1 temporary stoma.

CONCLUSIONS

  1. Surgical treatment of anorectal LC disease should be sparing and performed in the proper time. 2. Surgical treatment of anorectal LC disease is difficult and should be carried out in reference centers. 3. Anorectal LC disease has poor prognosis in terms of fecal and gas continence and creates the risk of proctectomy in up to 20% of cases.
摘要

未标注

作者回顾性分析了在华沙普通及胃肠外科接受手术治疗的肛门直肠型莱什尼夫斯基-克罗恩病(LC病)患者的手术结果。

材料与方法

1987年至2007年期间,我们共治疗了110例LC病患者。其中24例(13名女性,11名男性,平均发病年龄28岁)出现肛门直肠病变,占所有患者的21.8%。我们将其他医院实施的手术纳入考量范围,并将结果与文献数据进行比较。

结果

16/110例患者(14.5%)的肛门直肠病变是LC病的首发症状,最常见的病变为:12例多发肛周瘘、2例肛周脓肿、2例直肠阴道瘘。其余8例患者(7.3%)的肛门直肠病变出现在疾病后期,此前病变位于消化道其他部位。20/24例患者接受了一期局部手术治疗(切开/切除瘘管、脓肿引流)。最常见的手术指征为:13例肛周瘘、6例肛周脓肿、1例直肠阴道瘘。4/24例患者接受了一期腹部手术:2例直肠阴道瘘患者接受了哈特曼手术,另外2例重症结肠炎患者接受了全结肠切除术和保留直肠的结肠直肠切除术。23/24例患者的随访时间超过5年,仅1例患者为4年。19/24例(79.1%)患者出现手术复发。11例患者出现瘘管复发,此外,5例患者出现肛门狭窄,3例患者出现直肠/乙状结肠狭窄,3例患者出现残留直肠残端直肠炎。观察5年、10年和15年后,LC病的手术复发率分别为18/23(78.2%)、14/15(93.3%)和7/7(100%)。2例患者(8.3%)死于该疾病的严重全身并发症。仅2例患者一期局部手术治疗有效。18/22例患者在疾病后期接受了28次腹部手术。24例患者共接受了46次扩大腹部手术。结果,13/24例患者有永久性造口,1例患者有临时性造口。

结论

  1. 肛门直肠型LC病的手术治疗应谨慎,并在适当时间进行。2. 肛门直肠型LC病的手术治疗难度大,应在参考中心进行。3. 肛门直肠型LC病在粪便和气体节制方面预后较差,高达20%的病例有直肠切除风险。

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