Growdon Whitfield B, Del Carmen Marcela
Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Massachusetts General Hospital, Harvard Medical School Boston, MA.
Rev Obstet Gynecol. 2008 Fall;1(4):154-61.
The recent recognition of oncogenic human papillomavirus (HPV) as a key component of female lower genital tract malignancies has led to significant changes in many screening and prevention guidelines for cervical cancer, and, combined with the advent of vaccination, will likely have sweeping repercussions on the incidence of cervical, vulvar, and vaginal carcinoma. This article focuses on the specific principles of cancer screening and prevention with an emphasis on HPV-mediated disease.
近期,致癌性人乳头瘤病毒(HPV)被确认为女性下生殖道恶性肿瘤的关键组成部分,这使得许多宫颈癌筛查和预防指南发生了重大变化,并且,随着疫苗的问世,可能会对宫颈癌、外阴癌和阴道癌的发病率产生广泛影响。本文重点关注癌症筛查和预防的具体原则,尤其着重于HPV介导的疾病。