Jiang Hua, Cai Yun-qing, Qian Qiu-ying, Xun Peng-cheng, Wang Qiu-wei
Changzhou Women and Children Health Hospital, Changzhou 213003, China.
Zhonghua Liu Xing Bing Xue Za Zhi. 2008 Oct;29(10):982-4.
To investigate the relationship between maternal weight gain and the increasing speed of weight in different pregnant terms and macrosomia. In order to reasonably manage pregnancy and decrease the morbidity of macrosomia.
106 newborns whose birth weights were equal to or greater than 4000 g were specified as macrosomia, while 106 newborn with birth weights lying in 2500 - 3999 g were under the control group. A case-control study was conducted to compare the corresponding factors such as maternal BMI, weight before pregnancy and the change of weight during pregnancy respectively.
Indicated by both simple and multiple unconditional logistic regression analysis, the cause of fetal macrosomia was mainly associated with the factors including the maternal weight before pregnancy (OR = 2.204, 95%CI: 1.377 - 3.529), maternal weight gain in 12-pregnant weeks (kg per week) (OR = 1.961, 95%CI: 1.204 - 3.194), maternal weight gain in 20-gestation weeks (kg per week) (OR = 1.811, 95%CI: 1.078 - 3.041), maternal weight gain in 30-pregnant weeks (kg per week) (OR = 1.858, 95%CI: 1.095 - 3.153) and virile newborn (OR = 2.630, 95%CI: 1.420 - 4.850. When in 30-pregnant weeks, the pregnant women with 0.5 - 1.0 kg weight gain per week had 1.13 fold risks comparing to those whose weight gains were less than 0.5 kg per week.
Maternal weight before pregnancy, weight gain during pregnancy and fetal sex appeared a closer relation to macrosomia. It is necessary to monitor the change of maternal weight during different pregnancy periods, especially for the 30th-pregnant weeks.
探讨孕期体重增加及不同孕周体重增长速度与巨大儿的关系,以合理管理孕期,降低巨大儿发病率。
将出生体重≥4000g的106例新生儿定为巨大儿组,出生体重在2500~3999g的106例新生儿作为对照组,采用病例对照研究,分别比较两组孕妇的体质指数、孕前体重及孕期体重变化等相关因素。
单因素及多因素非条件logistic回归分析显示,胎儿巨大儿的发生主要与孕前体重(OR=2.204,95%CI:1.377~3.529)、孕12周体重增长速度(每周kg)(OR=1.961,95%CI:1.204~3.194)、孕20周体重增长速度(每周kg)(OR=1.811,95%CI:1.078~3.041)、孕30周体重增长速度(每周kg)(OR=1.858,95%CI:1.095~3.153)及男性新生儿(OR=2.630,95%CI:1.420~4.850)等因素有关。孕30周时,每周体重增加0.5~1.0kg的孕妇发生巨大儿的风险是每周体重增加不足0.5kg孕妇的1.13倍。
孕前体重、孕期体重增加及胎儿性别与巨大儿关系密切,孕期应监测孕妇不同孕周体重变化,尤其孕30周时。