Proksch E, Schnuch A, Uter W
Department of Dermatology, University of Kiel, Germany.
J Eur Acad Dermatol Venereol. 2009 Apr;23(4):388-93. doi: 10.1111/j.1468-3083.2008.03061.x.
Allergies to latex or 'rubber chemicals' in medical or other occupationally used gloves are not uncommon. In contrast, very few articles have reported on latex allergy (type I) or allergic contact sensitization to additives (type IV) associated with household gloves, in spite of some 44 million pairs sold in Germany in, e.g., 2006.
We seek to determine the frequency of allergies to household gloves by providing own data and we reviewed the literature.
The study was based on 105083 consultations of patients with suspected contact allergy (Type IV) in the Information Network of Departments of Dermatology (IVDK) in Germany in the years 1995 to 2006 and on the PubMed databases (last access 7/2008).
1221 patients were identified in whom protective gloves were considered as a possible cause of contact dermatitis and who did not work in occupations associated with above average risk of contact allergy to rubber chemicals. In 178 cases positive reactions to rubber components were reported, while 13 additional cases reacted only to a previously used rubber glove brand, but not to commercial allergens. In the literature only two publications on type I and two on type IV reactions were found in which allergies to rubber household gloves were explicitly reported.
Allergies to rubber household gloves seem to be rare. Factors presumably counteracting contact sensitization by household gloves, compared to occupational use, comprise short intermediate use, loose fitting and the incorporation of e.g. an inner cotton surface reducing skin contact with rubber chemicals.
对医用或其他职业用手套中的乳胶或“橡胶化学品”过敏并不罕见。相比之下,尽管2006年德国家用手套的销量约为4400万副,但关于家用手套引起的乳胶过敏(I型)或对添加剂的过敏性接触致敏(IV型)的报道却非常少。
我们通过提供自身数据来确定家用手套过敏的发生率,并对相关文献进行综述。
该研究基于1995年至2006年德国皮肤科部门信息网络(IVDK)中105083例疑似接触性过敏(IV型)患者的咨询记录以及PubMed数据库(最后访问时间为2008年7月)。
共识别出1221例患者,他们被认为接触性皮炎的可能病因是防护手套,且其职业不存在橡胶化学品接触过敏风险高于平均水平的情况。其中178例报告对橡胶成分有阳性反应,另有13例仅对之前使用过的某一品牌橡胶手套有反应,但对商用过敏原无反应。在文献中,仅发现两篇关于I型反应和两篇关于IV型反应的报道明确提及了对家用橡胶手套的过敏情况。
家用橡胶手套过敏似乎较为罕见。与职业使用相比,可能抵消家用手套引起接触致敏的因素包括使用时间短、佩戴宽松以及例如带有棉质内表面减少皮肤与橡胶化学品接触等。