Wilson D J, Franti C E, Norman B B
Department of Epidemiology and Preventive Medicine, School of Veterinary Medicine, University of California, Davis 95616.
J Am Vet Med Assoc. 1991 Aug 1;199(3):341-5.
Of 3,095 bob veal carcasses declared positive to the calf antibiotic and sulfonamide test (CAST) performed by USDA-FSIS personnel during the fiscal year 1988, 967 were submitted to USDA-FSIS laboratories for intensified antimicrobial evaluation of kidney, liver, and muscle specimens. In the western region, CAST-positive specimens were analyzed from certified calves, that is, calves declared free of antimicrobials by their producers. In the midwestern and eastern regions, 20% of the CAST-positive carcass submissions were certified and 20% had not been certified. Among the regions, neomycin was the most commonly reported agent from kidney specimens; however, there were some distinct differences among regions (24.6% of the specimens in the Midwest, 37.4% in the East, and 46.8% in the West). Reports of gentamicin in specimens also were different among regional laboratories (9.0% in the Midwest, 12.1% in the East, 3.1% in the West). Sulfamethazine was less frequently reported by the western laboratory, never exceeding 2% among the 3 tissues tested, whereas the eastern and midwestern laboratories had at least 1 tissue type that was greater than or equal to 9%. Not all specimens were subjected to sulfonamide evaluation. Regional patterns were noticed for unidentified microbial inhibitors, which were most evident for liver in which 24.6% of the specimens at the western laboratory were classified as having unidentified microbial inhibitors, and only 6.3% of specimens at the eastern laboratory were classified as having unidentified microbial inhibitors.
在1988财年由美国农业部食品安全检验局(USDA - FSIS)工作人员进行的小牛抗生素和磺胺类药物检测(CAST)中,3095头乳用小牛肉胴体被判定为阳性,其中967头被送往USDA - FSIS实验室,对肾脏、肝脏和肌肉样本进行强化抗菌评估。在西部地区,对经认证的小牛的CAST阳性样本进行了分析,即生产商宣称未使用抗菌药物的小牛。在中西部和东部地区,提交进行CAST检测的胴体中有20%是经认证的,20%未经过认证。在各地区中,新霉素是肾脏样本中最常报告的药物;然而,各地区之间存在一些明显差异(中西部地区样本的24.6%、东部地区的37.4%、西部地区的46.8%)。各地区实验室报告的庆大霉素在样本中的情况也有所不同(中西部地区为9.0%、东部地区为12.1%、西部地区为3.1%)。磺胺二甲嘧啶在西部实验室的报告频率较低,在测试的3种组织中从未超过2%,而东部和中西部实验室至少有一种组织类型的报告频率大于或等于9%。并非所有样本都进行了磺胺类药物评估。对于未鉴定的微生物抑制剂,发现了地区性模式,这在肝脏样本中最为明显,西部实验室24.6%的样本被归类为含有未鉴定的微生物抑制剂,而东部实验室只有6.3%的样本被归类为含有未鉴定的微生物抑制剂。