Hayashi Kentaro, Kitagawa Naoki, Morikawa Minoru, Hiu Takeshi, Morofuji Yoichi, Suyama Kazuhiko, Nagata Izumi
Department of Neurosurgery, Nagasaki University School of Medicine, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan.
Brain Nerve. 2009 Jan;61(1):83-7.
Recently, carotid artery stenting (CAS) has gained a lot of interest as a potentially valuable minimally invasive alternative to carotid endarterectomy. Since the occurrence of distal embolization as a result of CAS is still a major concern, an embolus protection device is usually employed during the procedure. Here, we report a case of internal carotid artery (ICA) stenosis complicated with shower embolism during CAS with an embolus protection filter. A 77-year-old man who had a history of coronary bypass surgery was referred to our department for the treatment of carotid artery stenosis. Angiography showed high-grade stenosis at the origin of the right ICA. Plaque magnetic resonance imaging (MRI) showed a hyperintense lesion at the right ICA stenosis, indicating the presence of a lipid-rich plaque. Since cerebral circulation was impaired significantly in the right cerebral hemisphere, CAS was performed for the right ICA stenosis, with an embolus protection filter. A self-expandable stent was placed in the right ICA following predilation. During stenting, plaque protrusion was identified and treated with balloon angioplasty. The patient developed right hemiparesis postoperatively. MRI showed multiple infarction in the right cerebral hemisphere. The symptom resoeved 7 days later. A potential disadvantage of the filter device is incomplete protection from emboli or failure to protect against soluble mediators. An embolus protection filter is not suitable for capturing the debris from lipid-rich plaques.
最近,作为颈动脉内膜切除术一种潜在的有价值的微创替代方法,颈动脉支架置入术(CAS)已引起广泛关注。由于CAS导致的远端栓塞仍是一个主要问题,因此在手术过程中通常会使用栓子保护装置。在此,我们报告1例在使用栓子保护滤器进行CAS期间发生颈内动脉(ICA)狭窄并伴有阵雨样栓塞的病例。一名有冠状动脉搭桥手术史的77岁男性因颈动脉狭窄被转诊至我科治疗。血管造影显示右侧ICA起始处存在高度狭窄。斑块磁共振成像(MRI)显示右侧ICA狭窄处有一个高强度病变,提示存在富含脂质的斑块。由于右侧大脑半球的脑循环明显受损,遂对右侧ICA狭窄进行了CAS,并使用了栓子保护滤器。预扩张后在右侧ICA置入了一个自膨式支架。在支架置入过程中,发现斑块突出并进行了球囊血管成形术治疗。患者术后出现右侧偏瘫。MRI显示右侧大脑半球有多处梗死。症状在7天后缓解。滤器装置的一个潜在缺点是对栓子的保护不完全或无法防止可溶性介质的影响。栓子保护滤器不适用于捕获富含脂质斑块的碎片。