[血管紧张素II和IV作为肾素-血管紧张素系统活性成分的生理作用]

[Physiological role of angiotensin II and IV as active components of the renin-angiotensin system].

作者信息

Prozherina Iu A

出版信息

Zh Vyssh Nerv Deiat Im I P Pavlova. 2008 Nov-Dec;58(6):649-62.

PMID:19178068

Abstract

A review. Modern concepts of the physiological role of basic active component of renin-angiotensin system angiotensin II and its 3-8 fragment angiotensin IV are stated. The basic ways of formation and further degradation of angiotensin II and IV in a body are described. General characteristic of physiological activity and possible mechanisms of action of angiotensin II and IV are presented. Specifically, the role of angiotensin II and IV in regulation of defensive and drinking behaviors of animals is considered.

摘要

综述。阐述了肾素 - 血管紧张素系统的基本活性成分血管紧张素II及其3 - 8片段血管紧张素IV生理作用的现代概念。描述了体内血管紧张素II和IV的形成及进一步降解的基本途径。介绍了血管紧张素II和IV生理活性的一般特征及其可能的作用机制。具体而言，探讨了血管紧张素II和IV在调节动物防御和饮水行为中的作用。