Weinel Sarah, Malone Janine, Jain Dharamvir, Callen Jeffrey P
Division of Dermatology, Department of Medicine, University of Louisville, Louisville, Kentucky, USA.
Australas J Dermatol. 2009 Feb;50(1):52-5. doi: 10.1111/j.1440-0960.2008.00504.x.
A 47-year-old woman with a history of breast cancer presented with eruptive cutaneous nodules on the trunk and extremities. Treatment for her breast cancer had included surgery, radiation and chemotherapy with doxorubicin and cyclophosphamide. Biopsy of the skin lesions revealed leukaemia cutis, which led to the discovery of acute myelogenous leukaemia. This was felt to be primarily induced by doxorubicin. Treatment included induction chemotherapy in preparation for a bone marrow transplant, which resulted in the disappearance of the cutaneous lesions. However, the patient later succumbed to her leukaemia.
一名有乳腺癌病史的47岁女性，躯干和四肢出现了暴发性皮肤结节。她的乳腺癌治疗包括手术、放疗以及使用阿霉素和环磷酰胺进行化疗。皮肤病变活检显示为皮肤白血病，进而发现了急性髓性白血病。认为这主要是由阿霉素诱发的。治疗包括为骨髓移植做准备的诱导化疗，这使得皮肤病变消失。然而，患者后来死于白血病。
