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[正常条件及饥饿状态下不同激素对大鼠脂肪组织脂肪分解作用的年龄特异性特征]

[Age-specific characteristics of the effect of various hormones on the lipolysis in the adipose tissue of rats under normal conditions and in starvation].

作者信息

Gatsko G G, Chaĭka L D

出版信息

Probl Endokrinol (Mosk). 1976 Sep-Oct;22(5):61-5.

PMID:191804
Abstract

Experiments were conducted in vitro; a study was mode of the age peculiarities attending be invluence of adrenaline, ACTH, STH on the lypolysis in the adipose tissue of rats under normal conditions and in starvation. During the process of ageing there occurs no change in the adipose tissue sensitivity to the action of hormones stimulating the lipolysis, but the capacity to react to high hormone doses is decreased. Elevation of the basal lypolysis in the adipose tissue of young rats occurs during starvation; the lypolytic action of the hormones falls. Starvation fails to alter the basal lypolysis in the adipose tissue to react to the hormone action.

摘要

实验在体外进行;研究了在正常条件和饥饿状态下,肾上腺素、促肾上腺皮质激素、生长激素对大鼠脂肪组织脂肪分解的年龄特异性影响。在衰老过程中,脂肪组织对刺激脂肪分解的激素作用的敏感性没有变化,但对高剂量激素的反应能力下降。饥饿期间,幼鼠脂肪组织的基础脂肪分解增加;激素的脂肪分解作用下降。饥饿不会改变脂肪组织对激素作用作出反应的基础脂肪分解。

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