Kawasaki Tomohiro, Koga Hisashi, Serikawa Takeshi, Orita Yoshiya, Ikeda Shinsuke, Mito Takahiro, Gotou Yoshitaka, Shintani Yoshiaki, Tanaka Atsushi, Tanaka Hidenori, Fukuyama Takaya, Koga Nobuhiko
Department of Cardiology, Cardiovascular Center, Shin-Koga Hospital, Kurume 830-8577, Japan.
Catheter Cardiovasc Interv. 2009 Apr 1;73(5):653-8. doi: 10.1002/ccd.21916.
Various two-stent techniques have been applied to aggressively treat bifurcation lesions as the introduction of drug-eluting stents (DES) and the importance of the bifurcation angle and three-dimensional (3D) structure has come to be recognized. Recent 64 multislice computed tomography (MSCT) technology provides accurate information about the 3D bifurcation geometry of the coronary arteries and with reproducibility.
The purpose of this study is to disclose the coronary bifurcation angle and 3D structure in humans and elucidate the importance of bifurcation angle for the crush technique using MSCT.
Two hundred and nine patients who were suspected to have angina pectoris and underwent CT angiography using MSCT were examined. The 3D-volume rendering (VR) image was reconstructed by two technicians and was used for the assessment of each coronary bifurcation angles.
The average LMT bifurcation angles (angle LMT-LAD, angle LMT-LCx, angle LAD-LCx) were 143 +/- 13 degrees , 121 +/- 21 degrees , and 72 +/- 22 degrees , respectively, the average angle LAD-D was 138 +/- 19 degrees , the average angle LCx-OM was 134 +/- 23 degrees , the average distal RCA bifurcation angles (angle RCA-4AV, angle RCA-4PD, angle 4AV-4PD) were 152 +/- 15 degrees , 137 +/- 20 degrees , and 61 +/- 21 degrees , respectively. In addition, a percentage of steep angled bifurcation (<110 degrees ) was significantly higher in the LMT (26%) than in other bifurcations (P < 0.05).
LMT bifurcation has been shown to have a higher rate of steep angled bifurcation in humans, it is therefore necessary to take the bifurcation angle into consideration in the case of LMT stenting. These data suggest that a bifurcation study using MSCT can clarify the 3D structure of coronary bifurcation and may provide useful information for bifurcation stenting.
随着药物洗脱支架(DES)的引入以及人们逐渐认识到分叉角度和三维(3D)结构的重要性,各种双支架技术已被应用于积极治疗分叉病变。最近的64层螺旋计算机断层扫描(MSCT)技术能够提供关于冠状动脉3D分叉几何结构的准确信息,且具有可重复性。
本研究旨在揭示人类冠状动脉分叉角度和3D结构,并阐明使用MSCT的挤压技术中分叉角度的重要性。
对209例疑似心绞痛并接受MSCT冠状动脉造影的患者进行检查。由两名技术人员重建3D容积再现(VR)图像,并用于评估每个冠状动脉分叉角度。
左主干(LMT)分叉平均角度(LMT-LAD角度、LMT-LCx角度、LAD-LCx角度)分别为143±13度、121±21度和72±22度,LAD-D平均角度为138±19度,LCx-OM平均角度为134±23度,右冠状动脉(RCA)远端分叉平均角度(RCA-4AV角度、RCA-4PD角度、4AV-4PD角度)分别为152±15度、137±20度和61±21度。此外,LMT处陡峭角度分叉(<110度)的百分比(26%)显著高于其他分叉处(P<0.05)。
已证明人类LMT分叉处陡峭角度分叉的发生率较高,因此在LMT置入支架时需要考虑分叉角度。这些数据表明,使用MSCT进行分叉研究可以阐明冠状动脉分叉的3D结构,并可能为分叉支架置入提供有用信息。