Aleman Monica, Nieto Jorge E, Benak Jaromir, Johnson Lynelle R
Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis 95616, USA.
J Am Vet Med Assoc. 2008 Oct 15;233(8):1302-6. doi: 10.2460/javma.233.8.1302.
To describe the clinical and laboratory findings, diagnostic features, and outcome of tracheal collapse in American Miniature Horses at a referral institution.
Retrospective case series.
13 American Miniature Horses with tracheal collapse.
Medical records of American Miniature Horses with tracheal collapse at a referral hospital were reviewed. Data extracted included signalment, history, clinical signs, laboratory data, diagnostic procedures, outcome, and histologic findings.
Tracheal collapse was documented in 5.6% of American Miniature Horses admitted to this referral hospital. Median age at onset of clinical signs was 11 years with a range of 2 to 15 years. Common complaints and clinical signs included respiratory distress, tachypnea, inspiratory honking noises, and increased abdominal expiratory effort, which were exacerbated by stressful events, pregnancy, exercise, a dusty environment, and eating. Tracheal collapse was confirmed by use of radiography, endoscopy, fluoroscopy, or postmortem examination. Dorsoventral flattening of the extra- or intrathoracic trachea, or both, was more common than lateral collapse. Tracheal chondromalacia was identified histologically in 4 cases, and mortality rate for affected horses was 10 of 13.
Tracheal collapse was relatively common in this study of American Miniature Horses, and outcome was poor. The etiopathogenesis of the disease remains unknown.
描述一家转诊机构中美系迷你马气管塌陷的临床和实验室检查结果、诊断特征及转归。
回顾性病例系列研究。
13例患有气管塌陷的美系迷你马。
回顾一家转诊医院中美系迷你马气管塌陷的病历。提取的数据包括特征、病史、临床症状、实验室数据、诊断程序、转归及组织学检查结果。
在这家转诊医院收治的美系迷你马中,气管塌陷的发生率为5.6%。出现临床症状的中位年龄为11岁,范围为2至15岁。常见主诉和临床症状包括呼吸窘迫、呼吸急促、吸气性鸣叫音以及腹部呼气用力增加,应激事件、妊娠、运动、多尘环境及进食会使这些症状加重。通过X线摄影、内镜检查、荧光镜检查或尸体剖检确诊气管塌陷。胸外或胸内气管或两者的背腹侧扁平比外侧塌陷更常见。4例在组织学上发现气管软骨软化,患病马匹的死亡率为13例中的10例。
在这项对美系迷你马的研究中,气管塌陷相对常见,且转归较差。该病的病因病机尚不清楚。