Marolf Angela, Blaik Margaret, Specht Andrew
Department of Small Animal Clinical Sciences, Veterinary Medical Center, University of Florida, 2015 SW 16th Avenue, PO Box 100102, Gainesville, USA.
Vet Radiol Ultrasound. 2007 May-Jun;48(3):199-203. doi: 10.1111/j.1740-8261.2007.00229.x.
Tracheal collapse is common in middle age toy and miniature breed dogs. Cartilaginous defects have been identified histologically and are considered a form of chondromalacia. In addition to tracheal cartilaginous changes, concurrent lower airway histologic changes indicative of inflammation have been noted in dogs with tracheal collapse and these changes may lead t o concurrent bronchiectasis. The purpose of this study was to investigate the prevalence of bronchiectasis in dogs with a previous radiographic diagnosis of tracheal collapse. The thoracic radiographs of 60 dogs with tracheal collapse were evaluated for evidence of concurrent bronchiectasis. Eighteen of 60 (30%) dogs had evidence of bronchiectasis, and all were cylindrical in morphology. The signalment of affected dogs was similar to that previously reported. The occurrence of bronchiectasis in this group of dogs with tracheal collapse (18 dogs) was six times higher (P < 0.05) than the expected prevalence within a random sample population (three dogs). The results of this study provide evidence of a link between tracheal collapse and bronchiectasis. A finding of bronchiectasis with tracheal collapse should encourage further evaluation for chronic lower airway disease in these patients.
气管塌陷在中年玩具犬和小型犬种中很常见。组织学上已确定存在软骨缺陷,这被认为是软骨软化的一种形式。除了气管软骨变化外,在气管塌陷的犬中还发现了同时存在的提示炎症的下呼吸道组织学变化,这些变化可能导致并发支气管扩张。本研究的目的是调查先前经放射学诊断为气管塌陷的犬中支气管扩张的患病率。对60只气管塌陷犬的胸部X光片进行评估,以寻找并发支气管扩张的证据。60只犬中有18只(30%)有支气管扩张的证据,且形态均为柱状。患病犬的特征与先前报道相似。这组气管塌陷犬(18只)中支气管扩张的发生率比随机抽样人群中的预期患病率(3只)高6倍(P < 0.05)。本研究结果为气管塌陷与支气管扩张之间的联系提供了证据。气管塌陷伴支气管扩张的发现应促使对这些患者进行慢性下呼吸道疾病的进一步评估。