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多发性骨髓瘤治疗模式的转变

Changing paradigms in the treatment of multiple myeloma.

作者信息

Bladé Joan, Rosiñol Laura

出版信息

Haematologica. 2009 Feb;94(2):163-6. doi: 10.3324/haematol.2008.002766.

DOI:10.3324/haematol.2008.002766
PMID:19181789
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2635403/
Abstract

The outcome of patients with multiple myeloma treated with conventional approaches has been unsatisfactory. In this perspective article, Drs. Bladé and Rosiñol examine the novel therapeutic options and their impact on the survival of these patients. See related paper on page 270.

摘要

采用传统方法治疗的多发性骨髓瘤患者的治疗效果一直不尽人意。在这篇观点文章中，布拉德博士和罗西尼奥尔博士探讨了新的治疗选择及其对这些患者生存的影响。见第270页的相关论文。

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本文引用的文献

1
Expected long-term survival of patients diagnosed with multiple myeloma in 2006-2010.2006年至2010年诊断为多发性骨髓瘤的患者的预期长期生存率。
Haematologica. 2009 Feb;94(2):270-5. doi: 10.3324/haematol.13782. Epub 2009 Jan 14.
2
Thalidomide-dexamethasone compared with melphalan-prednisolone in elderly patients with multiple myeloma.沙利度胺-地塞米松与美法仑-泼尼松在老年多发性骨髓瘤患者中的比较。
Blood. 2009 Apr 9;113(15):3435-42. doi: 10.1182/blood-2008-07-169565. Epub 2008 Oct 27.
3
Advances in therapy of multiple myeloma.多发性骨髓瘤的治疗进展
Curr Opin Oncol. 2008 Nov;20(6):697-704. doi: 10.1097/CCO.0b013e3283136984.
4
Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma.硼替佐米联合美法仑和泼尼松用于多发性骨髓瘤的初始治疗。
N Engl J Med. 2008 Aug 28;359(9):906-17. doi: 10.1056/NEJMoa0801479.
5
A prospective PETHEMA study of tandem autologous transplantation versus autograft followed by reduced-intensity conditioning allogeneic transplantation in newly diagnosed multiple myeloma.一项关于新诊断多发性骨髓瘤患者串联自体移植与自体移植后接受低强度预处理异基因移植的前瞻性PETHEMA研究。
Blood. 2008 Nov 1;112(9):3591-3. doi: 10.1182/blood-2008-02-141598. Epub 2008 Jul 8.
6
Multicenter, randomized, double-blind, placebo-controlled study of thalidomide plus dexamethasone compared with dexamethasone as initial therapy for newly diagnosed multiple myeloma.沙利度胺联合地塞米松与地塞米松作为新诊断多发性骨髓瘤初始治疗的多中心、随机、双盲、安慰剂对照研究
J Clin Oncol. 2008 May 1;26(13):2171-7. doi: 10.1200/JCO.2007.14.1853. Epub 2008 Mar 24.
7
Thalidomide for treatment of multiple myeloma: 10 years later.沙利度胺用于治疗多发性骨髓瘤：十年之后。
Blood. 2008 Apr 15;111(8):3968-77. doi: 10.1182/blood-2007-10-117457. Epub 2008 Feb 1.
8
Lenalidomide plus dexamethasone for relapsed multiple myeloma in North America.来那度胺联合地塞米松治疗北美复发多发性骨髓瘤
N Engl J Med. 2007 Nov 22;357(21):2133-42. doi: 10.1056/NEJMoa070596.
9
Lenalidomide plus dexamethasone for relapsed or refractory multiple myeloma.来那度胺联合地塞米松治疗复发或难治性多发性骨髓瘤。
N Engl J Med. 2007 Nov 22;357(21):2123-32. doi: 10.1056/NEJMoa070594.
10
Role of stem cell transplantation.干细胞移植的作用。
Hematol Oncol Clin North Am. 2007 Dec;21(6):1157-74, x. doi: 10.1016/j.hoc.2007.08.001.