多发性骨髓瘤治疗模式的转变
Changing paradigms in the treatment of multiple myeloma.
作者信息
Bladé Joan, Rosiñol Laura
出版信息
Haematologica. 2009 Feb;94(2):163-6. doi: 10.3324/haematol.2008.002766.
Abstract
The outcome of patients with multiple myeloma treated with conventional approaches has been unsatisfactory. In this perspective article, Drs. Bladé and Rosiñol examine the novel therapeutic options and their impact on the survival of these patients. See related paper on page 270.
摘要
采用传统方法治疗的多发性骨髓瘤患者的治疗效果一直不尽人意。在这篇观点文章中，布拉德博士和罗西尼奥尔博士探讨了新的治疗选择及其对这些患者生存的影响。见第270页的相关论文。
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本文引用的文献
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Thalidomide-dexamethasone compared with melphalan-prednisolone in elderly patients with multiple myeloma.沙利度胺-地塞米松与美法仑-泼尼松在老年多发性骨髓瘤患者中的比较。
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Advances in therapy of multiple myeloma.多发性骨髓瘤的治疗进展
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Bortezomib plus melphalan and prednisone for initial treatment of multiple myeloma.硼替佐米联合美法仑和泼尼松用于多发性骨髓瘤的初始治疗。
N Engl J Med. 2008 Aug 28;359(9):906-17. doi: 10.1056/NEJMoa0801479.
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A prospective PETHEMA study of tandem autologous transplantation versus autograft followed by reduced-intensity conditioning allogeneic transplantation in newly diagnosed multiple myeloma.一项关于新诊断多发性骨髓瘤患者串联自体移植与自体移植后接受低强度预处理异基因移植的前瞻性PETHEMA研究。
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