引发沉默。

Provocation of silence.

作者信息

van Opstal Jurren M, Volders Paul G A, Crijns Harry J G M

机构信息

Department of Cardiology, Maastricht University Medical Centre, P. Debyelaan 25, PO Box 5800, 6202 AZ Maastricht, The Netherlands.

出版信息

Europace. 2009 Mar;11(3):385-7. doi: 10.1093/europace/eun396. Epub 2009 Jan 30.

DOI:10.1093/europace/eun396

PMID:19181867

Abstract

We describe the development of a Brugada ECG together with sinus- and ventricular arrest after intravenous flecainide for atrial fibrillation in a patient in whom eventually a SCN5a mutation was identified. Unrecognized SCN5A mutations could underlie class IC-induced sinus arrest and conduction defects in some patients.

摘要

我们描述了一名患者在静脉注射氟卡尼治疗心房颤动后出现Brugada心电图以及窦性和心室停搏的情况，最终在该患者中发现了SCN5a突变。未被识别的SCN5A突变可能是某些患者中IC类药物诱发窦性停搏和传导缺陷的潜在原因。