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体内软组织的线性和非线性弹性成像:可行性证明

Linear and nonlinear elasticity imaging of soft tissue in vivo: demonstration of feasibility.

作者信息

Oberai Assad A, Gokhale Nachiket H, Goenezen Sevan, Barbone Paul E, Hall Timothy J, Sommer Amy M, Jiang Jingfeng

机构信息

Mechanical, Aerospace and Nuclear Engineering, Rensselaer Polytechnic Institute, Troy, NY 12180, USA.

出版信息

Phys Med Biol. 2009 Mar 7;54(5):1191-207. doi: 10.1088/0031-9155/54/5/006. Epub 2009 Jan 30.

Abstract

We establish the feasibility of imaging the linear and nonlinear elastic properties of soft tissue using ultrasound. We report results for breast tissue where it is conjectured that these properties may be used to discern malignant tumors from benign tumors. We consider and compare three different quantities that describe nonlinear behavior, including the variation of strain distribution with overall strain, the variation of the secant modulus with overall applied strain and finally the distribution of the nonlinear parameter in a fully nonlinear hyperelastic model of the breast tissue.

摘要

我们证实了使用超声对软组织的线性和非线性弹性特性进行成像的可行性。我们报告了对乳腺组织的研究结果,据推测这些特性可用于区分良性肿瘤和恶性肿瘤。我们考虑并比较了描述非线性行为的三种不同量,包括应变分布随总应变的变化、割线模量随总施加应变的变化,以及在乳腺组织的完全非线性超弹性模型中非线性参数的分布。

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