Maruyama Toru, Kadowaki Daisuke
Kumamoto University, Faculty of Pharmaceutical Sciences.
Clin Calcium. 2009 Feb;19(2):248-52.
Despite phosphate binders are necessary for the control of hyperphosphatemia in chronic kidney disease, adherence to medication tends to be low due to the lack of subjective symptoms of patients. Such non- adherence often causes compromised health outcomes. Key factors affecting adherence of phosphate binders are being the occurrence of side effects such as constipation, taking a lot of tablets, being lack of motive for medication. Thus, to facilitate the adherence of phosphate binders, it is recommended to select medication properly according to the situation of individual patients, to consider the side effect reduction and to raise motive of adherence by educational interventions and drug counseling.