Zheng Cai-Mei, Lu Kuo-Cheng, Wu Chia-Chao, Hsu Yung-Ho, Lin Yuh-Feng
Division of Nephrology, Department of Medicine, Taipei Medical University-Shuang Ho Hospital, Taipei Medical University, Taipei 235, Taiwan.
Int J Nephrol. 2011;2011:939613. doi: 10.4061/2011/939613. Epub 2011 May 25.
Vascular calcification is common in ESRD patients and is important in increasing mortality from cardiovascular complications in these patients. Hyperphosphatemia related to chronic kidney disease is increasingly known as major stimulus for vascular calcification. Hyperphosphatemia and vascular calcification become popular discussion among nephrologist environment more than five decades, and many researches have been evolved. Risk factors for calcification are nowadays focused for the therapeutic prevention of vascular calcification with the hope of reducing cardiovascular complications.
血管钙化在终末期肾病患者中很常见,并且在增加这些患者心血管并发症导致的死亡率方面具有重要意义。与慢性肾病相关的高磷血症日益被认为是血管钙化的主要刺激因素。高磷血症和血管钙化在肾脏病学领域已经成为热门讨论话题五十多年了,并且已经开展了许多研究。如今,钙化的危险因素聚焦于血管钙化的治疗性预防,以期降低心血管并发症。