Du Lin, Zhu Tianjiao, Li LiYuan, Cai Shengxin, Zhao Boyu, Gu Qianqun
Chinese Ministry of Education, School of Medicine and Pharmacy, Ocean University of China, Qindao, China.
Chem Pharm Bull (Tokyo). 2009 Feb;57(2):220-3. doi: 10.1248/cpb.57.220.
Four sorbicillinoids (1-4) and seven bisorbicillinoids (5-11), including two new compounds, 6-demethylsorbicillin (1) and 10,11-dihydrobisvertinolone (6), were isolated from a marine-derived fungus Trichoderma sp. Their cytotoxic activities against HL-60 cell line were evaluated by Sulforhodamine B (SRB) assay method and flow cytometric analysis.
从一株海洋来源的木霉菌Trichoderma sp.中分离得到了4种山梨素类化合物（1-4）和7种双山梨素类化合物（5-11），其中包括两种新化合物，6-去甲基山梨素（1）和10,11-二氢双弗维菌素（6）。采用磺酰罗丹明B（SRB）法和流式细胞术分析评估了它们对HL-60细胞系的细胞毒性活性。
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